In some types of human cancer, aldehyde dehydrogenases represent stemness markers
and their expression is associated with advanced disease stages and poor prognosis …

Docetaxel (DTX) is one of the important antitumor drugs, being used in several common
chemotherapies to control leading cancer types. Severe toxicities of the DTX are prominent …

Contact insecticides are primarily used for the control of Anopheles malaria vectors. These
chemicals penetrate mosquito legs and other appendages; the first barriers to reaching their …

Abstract Clinical development of 7-ethyl-10‑hydroxy-camptothecin (SN38), the active
metabolite of irinotecan (CPT-11), is hindered by its insolubility and poor stability. Another …

Retinoids represent a popular group of differentiation inducers that are successfully used in
oncology for treatment of acute promyelocytic leukemia in adults and of neuroblastoma in …

Background. According to relevant clinical research, dietary and circulating antioxidants
vitamin A are connected with the risk of breast, cervical, and ovarian cancer in women …

The tumor microenvironment orchestrates the sustained growth, metastasis and recurrence
of cancer. As an indispensable component of the tumor microenvironment, cancer …

Multidrug resistance (MDR) means that tumour cells become unresponsive during or after
the course of treatment to one or more of chemotherapeutic drugs. Chemotherapeutic …

ABCG2 is an exporter-type ABC protein that can expel numerous chemically unrelated xeno-
and endobiotics from cells. When expressed in tumor cells or tumor stem cells, ABCG2 …

Dietary flavonoids exhibit a variety of physiological functions in regulating glucose and lipid
metabolism, improving cardiovascular function, and enhancing stress resistance. However …