Repurposing existing drugs for the treatment of COVID-19/SARS-CoV-2 infection: A review describing drug mechanisms of action

H Yousefi, L Mashouri, SC Okpechi, N Alahari… - Biochemical …, 2021 - Elsevier
The outbreak of a novel coronavirus (SARS-CoV-2) has caused a major public health
concern across the globe. SARS-CoV-2 is the seventh coronavirus that is known to cause …

Comparative effects of different light sources on the production of key secondary metabolites in plants in vitro cultures

M Hashim, B Ahmad, S Drouet, C Hano, BH Abbasi… - Plants, 2021 - mdpi.com
Plant secondary metabolites are known to have a variety of biological activities beneficial to
human health. They are becoming more popular as a result of their unique features and …

Luteoloside attenuates neuroinflammation in focal cerebral ischemia in rats via regulation of the PPARγ/Nrf2/NF-κB signaling pathway

Q Li, Z Tian, M Wang, J Kou, C Wang, X Rong… - International …, 2019 - Elsevier
Luteoloside, a flavonoid compound, has been reported to have anti-inflammatory, anti-
oxidative, antibacterial, antiviral, anticancer, and cardioprotective effects, among others, but …

Chinese herbal medicine on cardiovascular diseases and the mechanisms of action

C Liu, Y Huang - Frontiers in pharmacology, 2016 - frontiersin.org
Cardiovascular diseases are the principal cause of death worldwide. The potentially serious
adverse effects of therapeutic drugs lead to growing awareness of the role of Chinese herbal …

[HTML][HTML] Natural sources, biological effects, and pharmacological properties of cynaroside

A Bouyahya, D Taha, T Benali, G Zengin… - Biomedicine & …, 2023 - Elsevier
Cynaroside is a flavonoid, isolated from several species belonging to the Apiaceae,
Poaceae, Lamiaceae, Solanaceae, Zingiberaceae, Compositae and other families and it …

Luteoloside suppresses proliferation and metastasis of hepatocellular carcinoma cells by inhibition of NLRP3 inflammasome

S Fan, Y Wang, J Lu, Y Zheng, D Wu, M Li, B Hu… - PloS one, 2014 - journals.plos.org
The inflammasome is a multi-protein complex which when activated regulates caspase-1
activation and IL-1β secretion. Inflammasome activation is mediated by NLR proteins that …

Low-dose strontium stimulates osteogenesis but high-dose doses cause apoptosis in human adipose-derived stem cells via regulation of the ERK1/2 signaling …

A Aimaiti, A Maimaitiyiming, X Boyong, K Aji… - Stem cell research & …, 2017 - Springer
Background Strontium is a widely used anti-osteoporotic agent due to its dual effects on
inhibiting bone resorption and stimulating bone formation. Thus, we studied the dose …

Isorhamnetin attenuates atherosclerosis by inhibiting macrophage apoptosis via PI3K/AKT activation and HO-1 induction

Y Luo, G Sun, X Dong, M Wang, M Qin, Y Yu, X Sun - PLoS One, 2015 - journals.plos.org
Background and Purpose Isorhamnetin (Iso) is a flavonoid compound extracted from the
Chinese herb Hippophae rhamnoides L. Previous studies have revealed its anti-cancer, anti …

[HTML][HTML] Effects of cynaroside on cell proliferation, apoptosis, migration and invasion though the MET/AKT/mTOR axis in gastric cancer

J Ji, Z Wang, W Sun, Z Li, H Cai, E Zhao… - International journal of …, 2021 - mdpi.com
The Chinese medicine monomer cynaroside (Cy) is a flavonoid glycoside compound that
widely exists in plants and has a variety of pharmacological effects, such as its important role …

Oxidative stress suppression by luteolin-induced heme oxygenase-1 expression

G Sun, X Sun, M Wang, J Ye, J Si, H Xu, X Meng… - Toxicology and Applied …, 2012 - Elsevier
Luteolin, a flavonoid that exhibits antioxidative properties, exerts myocardial protection
effects. However, the underlying molecular mechanisms are not yet fully understood. To …