Phenylboronic-tannin nanocolloids that scavenge subchondral reactive oxygen microenvironment and inhibit RANKL induced osteoclastogenesis for osteoarthritis …

X Li, Y Kou, J Jia, M Liu, R Gao, Y Li, G Li, S Xu… - Nano Research, 2024 - Springer
The excessive reactive oxygen species (ROS) accumulation and overactivated
osteoclastogenesis in subchondral bone has proved to be a major cause of osteoarthritis …

Bone-Targeted Supramolecular Nanoagonist Assembled by Accurate Ratiometric Herbal-Derived Therapeutics for Osteoporosis Reversal

Z Chang, D Chen, J Peng, R Liu, B Li, J Kang… - Nano Letters, 2024 - ACS Publications
Developing novel strategies for defeating osteoporosis has become a world-wide challenge
with the aging of the population. In this work, novel supramolecular nanoagonists (NAs) …

4-Hydroxyphenylacetic Acid, a microbial-derived metabolite of Polyphenols, inhibits osteoclastogenesis by inhibiting ROS production

Z Zhang, J Liu, Y Li, Y Wang, X Zheng, F Wang… - International …, 2024 - Elsevier
Intracellular reactive oxygen species (ROS) accumulation is key to osteoclast differentiation.
Plant-derived polyphenols that have reduced ROS production have been widely studied for …

Insight into Formation, Synchronized Release and Stability of Co-Amorphous Curcumin-Piperine by Integrating Experimental-Modeling Techniques

J Han, Y Yang, Y Hou, M Tang, Y Zhang, Y Zhu… - Journal of …, 2024 - Elsevier
Intermolecular interactions between drug and co-former are crucial in the formation, release
and physical stability of co-amorphous system. However, the interactions remain difficult to …

Development of paste-like organic/inorganic artificial bones compatible with bone remodeling cycles, consisting of β-tricalcium phosphate, calcium sulfate …

Y Kamaya, A Ando, K Suzuki, K Nakano… - New Journal of …, 2024 - pubs.rsc.org
Calcium-phosphate cement (CPC) is currently used to treat bone defects; however, it may
cause inflammation due to pH changes by acid–base reactions during setting. Therefore, we …