Antimicrobial resistance in Mycobacterium tuberculosis: mechanistic and evolutionary perspectives
Antibiotic-resistant Mycobacterium tuberculosis strains are threatening progress in
containing the global tuberculosis epidemic. Mycobacterium tuberculosis is intrinsically …
containing the global tuberculosis epidemic. Mycobacterium tuberculosis is intrinsically …
Drug resistant Tuberculosis: A review
JL Khawbung, D Nath, S Chakraborty - … immunology, microbiology and …, 2021 - Elsevier
Tuberculosis (TB) was announced as a global emergency in 1993. There was an alarming
counter attack of TB worldwide. However, when it was known that TB can be cured …
counter attack of TB worldwide. However, when it was known that TB can be cured …
Rapid scoring of genes in microbial pan-genome-wide association studies with Scoary
O Brynildsrud, J Bohlin, L Scheffer, V Eldholm - Genome biology, 2016 - Springer
Genome-wide association studies (GWAS) have become indispensable in human medicine
and genomics, but very few have been carried out on bacteria. Here we introduce Scoary …
and genomics, but very few have been carried out on bacteria. Here we introduce Scoary …
Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis
To characterize the genetic determinants of resistance to antituberculosis drugs, we
performed a genome-wide association study (GWAS) of 6,465 Mycobacterium tuberculosis …
performed a genome-wide association study (GWAS) of 6,465 Mycobacterium tuberculosis …
History of antimicrobial drug discovery: Major classes and health impact
R Aminov - Biochemical pharmacology, 2017 - Elsevier
The introduction of antibiotics into clinical practice revolutionized the treatment and
management of infectious diseases. Before the introduction of antibiotics, these diseases …
management of infectious diseases. Before the introduction of antibiotics, these diseases …
An overview of antimicrobial stewardship optimization: the use of antibiotics in humans and animals to prevent resistance
Antimicrobials are a type of agent widely used to prevent various microbial infections in
humans and animals. Antimicrobial resistance is a major cause of clinical antimicrobial …
humans and animals. Antimicrobial resistance is a major cause of clinical antimicrobial …
Microbial genome-wide association studies: lessons from human GWAS
The reduced costs of sequencing have led to whole-genome sequences for a large number
of microorganisms, enabling the application of microbial genome-wide association studies …
of microorganisms, enabling the application of microbial genome-wide association studies …
Pyseer: a comprehensive tool for microbial pangenome-wide association studies
Genome-wide association studies (GWAS) in microbes have different challenges to GWAS
in eukaryotes. These have been addressed by a number of different methods. pyseer brings …
in eukaryotes. These have been addressed by a number of different methods. pyseer brings …
[PDF][PDF] Current challenges in the management of sepsis in ICUs in resource-poor settings and suggestions for the future
MJ Schultz, MW Dünser, AM Dondorp… - … in resource-limited …, 2019 - library.oapen.org
In many low-and middle-income countries (LMICs), with improved public health services like
sanitation and immunization, the relative importance of curative care to improve health …
sanitation and immunization, the relative importance of curative care to improve health …
Machine learning and structural analysis of Mycobacterium tuberculosis pan-genome identifies genetic signatures of antibiotic resistance
Mycobacterium tuberculosis is a serious human pathogen threat exhibiting complex
evolution of antimicrobial resistance (AMR). Accordingly, the many publicly available …
evolution of antimicrobial resistance (AMR). Accordingly, the many publicly available …