[HTML][HTML] Solid-state NMR spectroscopy in pharmaceutical sciences

M Li, W Xu, Y Su - TrAC Trends in Analytical Chemistry, 2021 - Elsevier
Solid-state NMR (ssNMR) spectroscopy analyzes a wide range of pharmaceutical materials
in a non-disruptive and non-invasive manner. The obtained molecular properties at …

Mold inserts for injection molding prototype applications fabricated via material extrusion additive manufacturing

AM Gohn, D Brown, G Mendis, S Forster, N Rudd… - Additive …, 2022 - Elsevier
As extrusion-based 3D printers are easily accessible and quickly adopted, their application
to plastics manufacturing as a prototype development tool continues to expand. In …

Reverse engineering the Ozurdex dexamethasone intravitreal implant

MA Costello, J Liu, Y Wang, B Qin, X Xu, Q Li… - International Journal of …, 2023 - Elsevier
Ozurdex is a biodegradable implant formulated for sustained-release delivery of the
corticosteroid dexamethasone to the posterior segment of the eye. The small, rod-shaped …

Drug release mechanisms of high-drug-load, melt-extruded dexamethasone intravitreal implants

MA Costello, J Liu, B Chen, Y Wang, B Qin, X Xu… - European Journal of …, 2023 - Elsevier
Ozurdex is an FDA–approved sustained-release, biodegradable implant formulated to
deliver the corticosteroid dexamethasone to the posterior segment of the eye for up to 6 …

Development of hot-melt extruded drug/polymer matrices for sustained delivery of meloxicam

YC Chen, DE Moseson, CA Richard… - Journal of Controlled …, 2022 - Elsevier
For effective resolution of regional subacute inflammation and prevention of biofouling
formation, we have developed a polymeric implant that can release meloxicam, a selective …

Insights into Factors Affecting Ethylene-Vinyl Acetate Copolymer Crystallinity in Islatravir Implant

X Zhu, A Punia, D Skomski, Y Su, CS Shultz… - Molecular …, 2024 - ACS Publications
Islatravir, a highly potent nucleoside reverse transcriptase translocation inhibitor (NRTTI) for
the treatment of HIV, has great potential to be formulated as ethylene-vinyl acetate (EVA) …

Flexibility in drug product development: a perspective

Y Kapoor, RF Meyer, HM Ferguson… - Molecular …, 2021 - ACS Publications
The process of bringing a drug to market involves innumerable decisions to refine a concept
into a final product. The final product goes through extensive research and development to …

Dissolution from Ethylene Vinyl Acetate Copolymer Long-Acting Implants: Effect of Model Active Ingredient Size and Shape

AM Gohn, A Nolte, E Ravotti, SP Forster, M Giles… - Pharmaceutics, 2022 - mdpi.com
In recent pharmaceutical applications, an active pharmaceutical ingredient (API) can be
mixed with a polymer material to yield a composite long-acting drug-delivery device. These …

Dexamethasone intravitreal implants: characterization, manufacture, and elucidation of drug release mechanisms

MA Costello - 2023 - repositories.lib.utexas.edu
Long-acting injectable products based on the biodegradable polymer poly (lactide-co-
glycolide)(PLGA) have been available in the USA since 1989, with more than 20 PLGA …

[PDF][PDF] Dissolution from Ethylene Vinyl Acetate Copolymer Long-Acting Implants: Effect of Model Active Ingredient Size and Shape. Pharmaceutics 2022, 14, 1139

AM Gohn, A Nolte, E Ravotti, SP Forster, M Giles… - 2022 - academia.edu
In recent pharmaceutical applications, an active pharmaceutical ingredient (API) can be
mixed with a polymer material to yield a composite long-acting drug-delivery device. These …