Conventional methods for carrying out carbon–hydrogen functionalization and carbon–
nitrogen bond formation are typically conducted at elevated temperatures, and rely on …

The exploration of privileged structures in drug discovery is a rapidly emerging theme in
medicinal chemistry. These structures represent a class of molecules capable of binding to …

Organic molecules as well as metal complexes may exist as several geometric isomers1
which display distinct physical properties and chemical reactivities. A molecule containing …

The field of amino acids has gained enormous popularity and relevance in recent years,
particularly with the emergence of unnatural analogs as components of molecules with …

The electrochemical oxidation of amines is an essential alternative to the conventional
chemical transformation that provides critical routes for synthesising and modifying a wide …

R-Amino acids are one type of the main building blocks of living systems, being the principal
components of all naturally occurring peptides and proteins. Although only 20 compounds of …

Head-to-tail cyclic peptides have been reported to bind to multiple, unrelated classesof
receptor with high affinity. They may therefore be considered to beprivileged structures. This …

Electrochemistry constitutes a mild, green and versatile activation method of organic
molecules. Despite these innate advantages, its widespread use in organic chemistry has …

N-acyliminium ions are useful reactive synthetic intermediates in a variety of important
carbon–carbon bond forming and cyclisation strategies in organic chemistry. The advent of …

Anodic olefin coupling reactions using a tosylamine trapping group have been studied. The
cyclizations are favored by the use of a less-polar radical cation and more basic reaction …