Stroke is the second leading cause of mortality and the major cause of adult physical
disability worldwide. The currently available treatment to recanalize the blood flow in acute …

Ischemic stroke is a leading cause of disability and death in patients. Despite considerable
recent advances in the treatment of ischemic stroke, only a limited number of effective …

Background Ulinastatin, a urinary trypsin inhibitor, is one of the widely used auxiliary drugs
in the rescue of acute circulatory failure. This study aims to explore the protective …

Pachymic acid (PA) plays a neuroprotective role during cerebral ischemia/reperfusion.
However, the protective mechanisms of PA in cerebral ischemia/reperfusion have been not …

Neuropathic pain (NP) originating from a dysfunction in the nervous system is often
intractable and chronic. Many studies have implicated long noncoding RNAs (lncRNAs) in …

Ischemic stroke is one of the major causes of global mortality, which puts great demands on
health systems and social welfare. Ischemic stroke is a complex pathological process …

Alterations in the M1/M2 polarization phenotype significantly affect disease progression.
Antioxidant and anti-inflammatory protective effects of resveratrol (Res) have been …

The miRNAs and mRNAs are found to play a crucial role in modulating different diseases
including stroke, according to the recent evidence. The current study is aimed at assessing …

To date, studies have demonstrated the potential functions of microRNAs in cerebral
ischemia reperfusion (IR) injury. Herein, we established a middle cerebral artery occlusion …

Background: Transient Ischemia/Reperfusion (I/R) is the main reason for brain injury and
results in disruption of the Blood-Brain Barrier (BBB). It had been reported that BBB injury is …