A plethora of discoveries relating to sex influences on brain function is rapidly moving this
field into the spotlight for most areas of neuroscience. The domain of molecular or genetic …

The catalytic engine of RNA interference (RNAi) is the RNA-induced silencing complex
(RISC), wherein the endoribonuclease Argonaute and single-stranded small interfering RNA …

Translin, and its binding partner protein TRAX (translin-associated factor-X) are a
paralogous pair of conserved proteins, which have been implicated in a broad spectrum of …

Dysregulation of sleep and feeding has widespread health consequences. Despite
extensive epidemiological evidence for interactions between sleep and metabolic function …

Dysregulation of sleep or feeding has enormous health consequences. In humans, acute
sleep loss is associated with increased appetite and insulin insensitivity, while chronically …

Translin and Trax are components of an evolutionarily conserved RNA binding complex.
Deletion of Translin in yeast, Drosophila and mouse produces a dramatic loss of Trax …

Conserved translin–TRAX complexes, also known as C3POs, have been implicated in many
biological processes, but how they function remains unclear. Recently, C3PO was shown to …

Translin is a conserved protein which associates with the breakpoint junctions of
chromosomal translocations linked with the development of some human cancers. It binds to …

Translin, a highly conserved, DNA/RNA binding protein, is abundantly expressed in brain,
testis and in certain malignancies. It was discovered initially in the quest to find proteins that …

Translin protein is highly conserved in eukaryotes. Human translin binds both ssDNA and
RNA. Its nucleic acid binding site results from a combination of basic regions in the …