Radiotracers for Imaging of Inflammatory Biomarkers TSPO and COX-2 in the Brain and in the Periphery

BC Uzuegbunam, C Rummel, D Librizzi… - International Journal of …, 2023 - mdpi.com
Inflammation involves the activation of innate immune cells and is believed to play an
important role in the development and progression of both infectious and non-infectious …

Probing immune infiltration dynamics in cancer by in vivo imaging

TSC Ng, HH Allen, M Rashidian, MA Miller - Current opinion in chemical …, 2022 - Elsevier
Cancer immunotherapies typically aim to stimulate the accumulation and activity of cytotoxic
T-cells or pro-inflammatory antigen-presenting cells, reduce immunosuppressive myeloid …

Total-body multiparametric PET quantification of 18F-FDG delivery and metabolism in the study of coronavirus disease 2019 recovery

Y Wang, L Nardo, BA Spencer… - Journal of Nuclear …, 2023 - Soc Nuclear Med
Conventional whole-body static 18F-FDG PET imaging provides a semiquantitative
evaluation of overall glucose metabolism without insight into the specific transport and …

[HTML][HTML] Glial suppression and post-traumatic stress disorder: a cross-sectional study of 1,520 world trade center responders

G Natale, M Kritikos, PF Kuan, MA Carr, X Yang… - Brain, Behavior, & …, 2023 - Elsevier
Background Chronically re-experiencing the memory of a traumatic event might cause a
glial response. This study examined whether glial activation would be associated with PTSD …

Overview of positron emission tomography in functional imaging of the lungs for diffuse lung diseases

AV Gulhane, DL Chen - The British Journal of Radiology, 2022 - academic.oup.com
Positron emission tomography (PET) is a quantitative molecular imaging modality
increasingly used to study pulmonary disease processes and drug effects on those …

[HTML][HTML] Novel TSPO Ligand 2-Cl-MGV-1 Can Counteract Lipopolysaccharide Induced Inflammatory Response in Murine RAW264. 7 Macrophage Cell Line and Lung …

F Obeid, M Kahana, B Dahle, S Monga, Y Zohar… - Cells, 2024 - mdpi.com
We assessed the anti-inflammatory activity of the TSPO ligand 2-Cl-MGV-1.
Lipopolysaccharide (LPS) was used to induce inflammatory response in a murine RAW264 …

Molecular imaging of inflammation with PET in acute and ventilator-induced lung injury

G Musch - Frontiers in Physiology, 2023 - frontiersin.org
This review focuses on methods to image acute lung inflammation with Positron Emission
Tomography (PET). Four approaches are discussed that differ for biologic function of the …

Non-invasive quantification of acute macrophagic lung inflammation with [11C](R)-PK11195 using a three-tissue compartment kinetic model in experimental acute …

L Bitker, F Dhelft, S Lancelot, D Le Bars… - European Journal of …, 2022 - Springer
Purpose Imaging of acute lung inflammation is pivotal to evaluate innovative ventilation
strategies. We aimed to develop and validate a three-tissue compartment kinetic model …

OPEN ACCESS EDITED BY

JM Reinhardt, ARS Carvalho, K Vaporidi… - … Imaging of the Lung, 2024 - books.google.com
OPEN ACCESS EDITED BY Page 44 TYPE Review frontiers Frontiers in Physiology
PUBLISHED 21 March 2023 DOI 10.3389/fphys. 2023.1142221 Check for updates OPEN …

Nuclear Imaging of Inflammation

G Keeling, F Man - Imaging Inflammation, 2023 - Springer
Nuclear imaging can be a powerful tool for imaging inflammation, for research and clinical
use. Nuclear imaging methods allow noninvasive visualization of biochemical processes …