The harmonizome: a collection of processed datasets gathered to serve and mine knowledge about genes and proteins
AD Rouillard, GW Gundersen, NF Fernandez… - Database, 2016 - academic.oup.com
Genomics, epigenomics, transcriptomics, proteomics and metabolomics efforts rapidly
generate a plethora of data on the activity and levels of biomolecules within mammalian …
generate a plethora of data on the activity and levels of biomolecules within mammalian …
SpermBase: a database for sperm-borne RNA contents
Since their discovery approximately three decades ago, sperm-borne RNAs, both
large/small and coding/noncoding, have been reported in multiple organisms, and some …
large/small and coding/noncoding, have been reported in multiple organisms, and some …
Intelligent and effective informatic deconvolution of “Big Data” and its future impact on the quantitative nature of neurodegenerative disease therapy
Biomedical data sets are becoming increasingly larger and a plethora of high-dimensionality
data sets (“Big Data”) are now freely accessible for neurodegenerative diseases, such as …
data sets (“Big Data”) are now freely accessible for neurodegenerative diseases, such as …
High-dimensionality data analysis of pharmacological systems associated with complex diseases
It is widely accepted that molecular reductionist views of highly complex human physiologic
activity, eg, the aging process, as well as therapeutic drug efficacy are largely …
activity, eg, the aging process, as well as therapeutic drug efficacy are largely …
[HTML][HTML] GOsummaries: an R package for visual functional annotation of experimental data
Functional characterisation of gene lists using Gene Ontology (GO) enrichment analysis is a
common approach in computational biology, since many analysis methods end up with a list …
common approach in computational biology, since many analysis methods end up with a list …
Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy
M Georganaki, M Ramachandran, S Tuit… - …, 2020 - Taylor & Francis
ABSTRACT CD40-stimulating immunotherapy can elicit potent anti-tumor responses by
activating dendritic cells and enhancing T-cell priming. Tumor vessels orchestrate T-cell …
activating dendritic cells and enhancing T-cell priming. Tumor vessels orchestrate T-cell …
Hippocampal transcriptomic and proteomic alterations in the BTBR mouse model of autism spectrum disorder
CM Daimon, JM Jasien, WH Wood III, Y Zhang… - Frontiers in …, 2015 - frontiersin.org
Autism spectrum disorders (ASD) are complex heterogeneous neurodevelopmental
disorders of an unclear etiology, and no cure currently exists. Prior studies have …
disorders of an unclear etiology, and no cure currently exists. Prior studies have …
Wormicloud: a new text summarization tool based on word clouds to explore the C. elegans literature
V Arnaboldi, J Cho, PW Sternberg - Database, 2021 - academic.oup.com
Finding relevant information from newly published scientific papers is becoming increasingly
difficult due to the pace at which articles are published every year as well as the increasing …
difficult due to the pace at which articles are published every year as well as the increasing …
PMIDigest: interactive review of large collections of PubMed entries to distill relevant information
Scientific knowledge is being accumulated in the biomedical literature at an unprecedented
pace. The most widely used database with biomedicine-related article abstracts, PubMed …
pace. The most widely used database with biomedicine-related article abstracts, PubMed …
The compressed vocabulary of microbial life
G Caetano-Anollés - Frontiers in Microbiology, 2021 - frontiersin.org
Communication is an undisputed central activity of life that requires an evolving molecular
language. It conveys meaning through messages and vocabularies. Here, I explore the …
language. It conveys meaning through messages and vocabularies. Here, I explore the …