Colorectal cancer (CRC) is still one of the most common types of cancer in the world, and
the gut microbiome plays an important role in its development. The microbiome is involved …

Simple Summary Although comprising a much smaller proportion of the human microbiome,
the fungal community has gained much more attention lately due to its multiple and yet …

Intestinal stem cells (ISCs) play an important role in maintaining intestinal homeostasis via
promoting a healthy gut barrier. Within the stem cell niche, gut microbiota linking the …

Colorectal cancer (CRC) is ranked as the second most common cause of cancer deaths and
the third most common cancer globally. It has been described as a 'silent disease'which is …

Invasion involves tumor cells altering their cell-matrix interactions and acquiring motility for
metastatic spread. Invasive tumor cells exhibit dysregulated metabolism and enhanced …

Simple Summary Obesity is associated with an increased risk of colorectal cancer (CRC).
Recent studies suggest that gut dysbiosis, ie, abnormal perturbations in the gut microbiome …

Colorectal cancer is one of the most commonly diagnosed cancers worldwide. Traditionally,
mechanisms of colorectal cancer formation have focused on genetic alterations including …

Cancer is a major disease endangering human health. More and more studies have shown
that microorganisms play an extremely important role in the occurrence, development and …

PIK3CA mutations are amongst the most prevalent somatic mutations in cancer and are
associated with resistance to first-line treatment along with low survival rates in a variety of …

Simple Summary In the past decade, the interaction between intestinal microbiota and
colorectal cancer has been an active research area. Microbial metabolites, which could act …