Mast cells and interleukins

AG Solimando, V Desantis, D Ribatti - International Journal of Molecular …, 2022 - mdpi.com
Mast cells play a critical role in inflammatory diseases and tumor growth. The versatility of
mast cells is reflected in their ability to secrete a wide range of biologically active cytokines …

Mast cells in food allergy: Inducing immediate reactions and shaping long-term immunity

HC Oettgen - Journal of Allergy and Clinical Immunology, 2023 - Elsevier
Mast cells are distributed throughout the gastrointestinal tract and function as the main
effector cells of IgE-mediated allergic reactions to foods. Allergen-induced cross-linking of …

Mast cell secretome: Soluble and vesicular components

KV Vukman, A Försönits, A Oszvald, EA Toth… - Seminars in Cell & …, 2017 - Elsevier
Mast cells are multifunctional master cells implicated in both innate and adaptive immune
responses. Their role has been best characterized in allergy and anaphylaxis; however …

Immune mediators of chronic pelvic pain syndrome

SF Murphy, AJ Schaeffer, P Thumbikat - Nature Reviews Urology, 2014 - nature.com
The cause of chronic pelvic pain syndrome (CPPS) has yet to be established. Since the late
1980s, cytokine, chemokine, and immunological classification studies using human samples …

The tetraspanin CD63 is required for efficient IgE-mediated mast cell degranulation and anaphylaxis

S Kraft, MH Jouvin, N Kulkarni, S Kissing… - The Journal of …, 2013 - journals.aai.org
Mast cell (MC) activation through the high-affinity IgE receptor FcεRI leads to the release of
mediators involved in immediate-type allergic reactions. Although Abs against the …

Roles for Ca2+ Mobilization and Its Regulation in Mast Cell Functions

D Holowka, N Calloway, R Cohen, D Gadi… - Frontiers in …, 2012 - frontiersin.org
Mobilization of Ca2+ in response to IgE receptor-mediated signaling is a key process in
many aspects of mast cell function. Here we summarize our current understanding of the …

Surface TLR2 and TLR4 expression on mature rat mast cells can be affected by some bacterial components and proinflammatory cytokines

A Pietrzak, M Wierzbicki, M Wiktorska… - Mediators of …, 2011 - Wiley Online Library
The aim of our study was to determine whether some bacterial components as well as some
proinflammatory cytokines can affect surface mast cell levels. By the use of flow cytometry …

Anti-allergic properties of a matured fruit extract of the date palm tree (Phoenix dactylifera L.) in mite-sensitized mice

K Karasawa, H Otani - Journal of nutritional science and …, 2012 - jstage.jst.go.jp
MATERIALS AND METHODS Materials. Phycoerythrin (PE)-labeled anti-mouse IL-4
monoclonal antibody (mAb, clone 11B11), PE-labeled anti-mouse IFN-mAb (clone XMG1 …

Type 1 diabetes in NOD mice unaffected by mast cell deficiency

DA Gutierrez, W Fu, S Schonefeldt, TB Feyerabend… - Diabetes, 2014 - Am Diabetes Assoc
Mast cells have been invoked as important players in immune responses associated with
autoimmune diseases. Based on in vitro studies, or in vivo through the use of Kit mutant …

Anti‐allergic effects of Lactobacillus crispatus KT‐11 strain on ovalbumin‐sensitized BALB/c mice

K Tobita, H Yanaka, H Otani - Animal science journal, 2010 - Wiley Online Library
In this study, we investigated the effects of oral ingestion of Lactobacillus crispatus KT‐11
strain (KT‐11) on the immune response in an allergic rhinitis mouse model, ovalbumin …