Diabetic peripheral neuropathy (DPN) refers to the development of peripheral nerve
dysfunction in patients with diabetes when other causes are excluded. Diabetic distal …

Spinal muscular atrophy (SMA) is an autosomal recessive genetic disorder leading to
paralysis, muscle atrophy, and death. Significant advances in antisense oligonucleotide …

In the polyol pathway, aldose reductase (AR) catalyzes the formation of sorbitol from
glucose. In order to detoxify some dangerous aldehydes, AR is essential. However, due to …

Background Skeletal muscle atrophy, whether caused by chronic disease, acute critical
illness, disuse or aging, is characterized by tissue-specific decrease in oxidative capacity …

Neurogenic atrophy refers to the loss of muscle mass and function that results directly from
injury or disease of the peripheral nervous system. Individuals with neurogenic atrophy may …

(1) Background: Female sex is considered a risk factor for Intensive Care Unit-Acquired
Weakness (ICUAW). The aim is to investigate sex-specific aspects of skeletal muscle …

Diabetic painful neuropathy (DPN) is one of the most detrimental complications of diabetes.
Alterations in neuroinflammatory mediators play significant roles in the development of DPN …

Background The oral and pharyngeal jaw of cichlid fishes are a classic example of
evolutionary modularity as their functional decoupling boosted trophic diversification and …

Desminopathy is the most common intermediate filament disease in humans. The most
frequent mutation causing desminopathy in patients is a R350P DES missense mutation. We …

Skeletal muscle atrophy is a condition characterized by a loss of muscle mass and muscle
strength caused by an imbalance between protein synthesis and protein degradation …