New insights in pathogenesis of endometriosis

PG Signorile, R Viceconte, A Baldi - Frontiers in medicine, 2022 - frontiersin.org
Endometriosis is a gynecological disease characterized by the growth of endometrial glands
and stroma outside the uterine cavity. The incidence of the disease is very high, there are …

Endometriosis and risk of ovarian cancer: what do we know?

M Králíčková, AS Laganà, F Ghezzi… - Archives of gynecology and …, 2020 - Springer
Purpose Despite long and intensive research, endometriosis remains one of the leading
causes of morbidity among premenopausal women. The majority of endometriosis-related …

Therapeutic approaches of resveratrol on endometriosis via anti-inflammatory and anti-angiogenic pathways

AM Dull, MA Moga, OG Dimienescu, G Sechel… - Molecules, 2019 - mdpi.com
Endometriosis represents a severe gynecological pathology, defined by implantation of
endometrial glands and stroma outside the uterine cavity. This pathology affects almost 15 …

Human disease-drug network based on genomic expression profiles

G Hu, P Agarwal - PloS one, 2009 - journals.plos.org
Background Drug repositioning offers the possibility of faster development times and
reduced risks in drug discovery. With the rapid development of high-throughput technologies …

miRNA‐199a‐5p regulates VEGFA in endometrial mesenchymal stem cells and contributes to the pathogenesis of endometriosis

CY Hsu, TH Hsieh, CF Tsai, HP Tsai… - The Journal of …, 2014 - Wiley Online Library
It is believed that endometrial miRNAs contribute to the aetiology of endometriosis in stem
cells; however, the mechanisms remain unclear. Here we collected serum samples from …

[HTML][HTML] Comparative study of human eutopic and ectopic endometrial mesenchymal stem cells and the development of an in vivo endometriotic invasion model

AP Kao, KH Wang, CC Chang, JN Lee, CY Long… - Fertility and sterility, 2011 - Elsevier
OBJECTIVE: To elucidate the role of endometrial stem-progenitor cells in the etiology of
endometriosis and to develop an animal model to study the invasion ability of endometrial …

Endometriosis: new concepts in the pathogenesis

PG Signorile, A Baldi - The international journal of biochemistry & cell …, 2010 - Elsevier
Endometriosis is a gynaecological disease defined by the histological presence of
endometrial glands and stroma outside the uterine cavity. Though there are several theories …

Autophagy and mitophagy promotion in a rat model of endometriosis

R Siracusa, R D'Amico, D Impellizzeri… - International Journal of …, 2021 - mdpi.com
Endometriosis is a gynecological condition affecting patients in reproductive age. The aim of
this paper was to assess the effects of the autophagy and mitophagy induction in a rat model …

Pre-natal exposure of mice to bisphenol A elicits an endometriosis-like phenotype in female offspring

PG Signorile, EP Spugnini, L Mita, P Mellone… - General and …, 2010 - Elsevier
Endometriosis is a chronic gynecological disease characterized by the growth of
endometrial tissue outside the uterine cavity. Exposure to endocrine disruptors during critical …

Higher expression of vascular endothelial growth factor (VEGF) and its receptor VEGFR-2 (Flk-1) and metalloproteinase-9 (MMP-9) in a rat model of peritoneal …

DE Machado, PT Berardo, CY Palmero… - Journal of Experimental & …, 2010 - Springer
Background Endometriosis is a common disease characterized by the presence of a
functional endometrium outside the uterine cavity, causing pelvic pain, dysmenorrheal, and …