Emerging roles of tRNA-derived fragments in cancer
M Fu, J Gu, M Wang, J Zhang, Y Chen, P Jiang, T Zhu… - Molecular cancer, 2023 - Springer
Abstract tRNA-derived fragments (tRFs) are an emerging category of small non-coding
RNAs that are generated from cleavage of mature tRNAs or tRNA precursors. The advance …
RNAs that are generated from cleavage of mature tRNAs or tRNA precursors. The advance …
On the expanding roles of tRNA fragments in modulating cell behavior
R Magee, I Rigoutsos - Nucleic acids research, 2020 - academic.oup.com
The fragments that derive from transfer RNAs (tRNAs) are an emerging category of
regulatory RNAs. Known as tRFs, these fragments were reported for the first time only a …
regulatory RNAs. Known as tRFs, these fragments were reported for the first time only a …
Meta-analysis of tRNA derived RNA fragments reveals that they are evolutionarily conserved and associate with AGO proteins to recognize specific RNA targets
Background tRFs, 14 to 32 nt long single-stranded RNA derived from mature or precursor
tRNAs, are a recently discovered class of small RNA that have been found to be present in …
tRNAs, are a recently discovered class of small RNA that have been found to be present in …
Deciphering the tRNA-derived small RNAs: origin, development, and future
Transfer RNA (tRNA)-derived small RNAs (tsRNAs), a novel category of small noncoding
RNAs, are enzymatically cleaved from tRNAs. Previous reports have shed some light on the …
RNAs, are enzymatically cleaved from tRNAs. Previous reports have shed some light on the …
Human tRNA-derived small RNAs in the global regulation of RNA silencing
D Haussecker, Y Huang, A Lau, P Parameswaran… - Rna, 2010 - rnajournal.cshlp.org
Competition between mammalian RNAi-related gene silencing pathways is well
documented. It is therefore important to identify all classes of small RNAs to determine their …
documented. It is therefore important to identify all classes of small RNAs to determine their …
Paternal contributions to offspring health: role of sperm small RNAs in intergenerational transmission of epigenetic information
U Sharma - Frontiers in cell and developmental biology, 2019 - frontiersin.org
The most fundamental process for the perpetuation of a species is the transfer of information
from parent to offspring. Although genomic DNA contributes to the majority of the …
from parent to offspring. Although genomic DNA contributes to the majority of the …
[HTML][HTML] Stressing out over tRNA cleavage
DM Thompson, R Parker - Cell, 2009 - cell.com
A conserved response to stress involves endonucleolytic cleavage of cytoplasmic transfer
RNAs (tRNAs) by ribonucleases that are normally secreted or sequestered. Ribonuclease …
RNAs (tRNAs) by ribonucleases that are normally secreted or sequestered. Ribonuclease …
A tRNA fragment, 5′-tiRNAVal, suppresses the Wnt/β-catenin signaling pathway by targeting FZD3 in breast cancer
D Mo, P Jiang, Y Yang, X Mao, X Tan, X Tang, D Wei… - Cancer letters, 2019 - Elsevier
Abstract tRNA-derived fragments offer a recently identified group of non-coding single-
stranded RNAs that are often as abundant as microRNAs in cancer cells and play important …
stranded RNAs that are often as abundant as microRNAs in cancer cells and play important …
RNA granules: the good, the bad and the ugly
MG Thomas, M Loschi, MA Desbats, GL Boccaccio - Cellular signalling, 2011 - Elsevier
Processing bodies (PBs) and Stress Granules (SGs) are the founding members of a new
class of RNA granules, known as mRNA silencing foci, as they harbour transcripts …
class of RNA granules, known as mRNA silencing foci, as they harbour transcripts …