Osteoporosis is caused by the disruption in homeostasis between bone formation and bone
resorption. Conventional management of osteoporosis involves systematic drug …

Fibrin, derived from proteins involved in blood clotting (fibrinogen and thrombin), is a
biopolymer with different applications in the health area since it has hemostasis …

Cell therapy strategies using mesenchymal stem cells (MSCs) carried in fibrin glue have
shown promising results in regenerative medicine. MSCs are crucial for tissue healing …

Articular cartilage defects are one of the major challenges in orthopedic and trauma surgery.
However, the poor ability of cartilage to self-repair has motivated efforts to engineer …

There are several treatment methods available for bone repair, although the effectiveness
becomes limited in cases of large defects. The objective of this pre-clinical protocol was to …

Background Heterologous fibrin sealant (HFS) consists of a fibrinogen-rich cryoprecipitate
extracted from Bubalus bubalis buffalo blood and a thrombin-like enzyme purified from …

The aim is to evaluate the effects of photobiomodulation therapy (PBMT) on the guided bone
regeneration process (GBR) in defects in the calvaria of rats filled with biphasic calcium …

The use of low-level laser therapy (LLLT) with biomodulatory effects on biological tissues,
currently called photobiomodulation therapy (PBMT), assists in healing and reduces …

Background: Bone tissue repair remains a challenge in tissue engineering. Currently, new
materials are being applied and often integrated with live cells and biological scaffolds. The …

Fibrin biopolymers, previously referred as “fibrin glue” or “fibrin sealants”, are natural
biomaterials with diverse applications on health. They have hemostatic, adhesive, sealant …