Prevalence and role of HER2 mutations in cancer

E Cocco, S Lopez, AD Santin, M Scaltriti - Pharmacology & therapeutics, 2019 - Elsevier
HER2 activating mutations act as oncogenic drivers in various cancer types. In the clinic,
they can be identified by next generation sequencing (NGS) in either tumor biopsies or …

BK virus: current understanding of pathogenicity and clinical disease in transplantation

S Chong, M Antoni, A Macdonald… - Reviews in Medical …, 2019 - Wiley Online Library
BK polyomavirus (BKV) is an important cause of graft loss in renal transplant recipients that
continues to pose a significant challenge to clinicians due to its frequently unpredictable …

Potential urinary extracellular vesicle protein biomarkers of chronic active antibody-mediated rejection in kidney transplant recipients

HY Jung, CH Lee, JY Choi, JH Cho, SH Park… - … of Chromatography B, 2020 - Elsevier
The aim of this study was to identify potential proteomic biomarkers for chronic active
antibody-mediated rejection (CAMR) in kidney transplant recipients (KTRs). Among 385 …

Intrapatient variability in tacrolimus trough levels over 2 years affects long-term allograft outcomes of kidney transplantation

Y Park, H Lee, SH Eum, HD Kim, EJ Ko… - Frontiers in …, 2021 - frontiersin.org
This study aimed to determine the impact of tacrolimus (TAC) trough level (C0) intrapatient
variability (IPV) over a period of 2 years after kidney transplantation (KT) on allograft …

[HTML][HTML] Incidence, risk factors, and outcome of BK polyomavirus infection after kidney transplantation

E Favi, C Puliatti, R Sivaprakasam… - World journal of …, 2019 - ncbi.nlm.nih.gov
BACKGROUND Polyomavirus-associated nephropathy is a leading cause of kidney allograft
failure. Therapeutic options are limited and prompt reduction of the net state of …

Evaluating the efficiency of the Cobas 6800 system for BK virus detection in plasma and urine samples

J Song, S Kim, E Kwak, Y Park - Diagnostics, 2023 - mdpi.com
We evaluated the overall performance of the Cobas 6800 BKV test in detecting BK virus
(BKV). We examined the imprecision of the Cobas 6800 BKV test and compared the …

Urine exosomal bkv-miR-B1-5p and BK virus nephropathy in kidney transplant recipients

SW Jung, WH Cho, JW Seo, YG Kim… - The Journal of …, 2023 - academic.oup.com
Background Urine exosomal bkv-miR-B1-5p is associated with BK virus (BKV) nephropathy
(BKVN); however, its posttransplantation changes and predictability for BKVN have not been …

Development of a droplet digital PCR assay for the detection of BK polyomavirus

L Ai, Y Zhao, C Tan, L Bai, G Huang, R Wang… - Microbiology …, 2024 - journals.asm.org
The objective of this study was to establish a more sensitive and specific diagnostic method
for detecting plasma BK polyomavirus (BKPyV) DNA load in patients after renal …

The role of HLA and KIR immunogenetics in BK virus infection after kidney transplantation

M Burek Kamenaric, V Ivkovic, I Kovacevic Vojtusek… - Viruses, 2020 - mdpi.com
BK virus (BKV) is a polyomavirus with high seroprevalence in the general population with an
unremarkable clinical presentation in healthy people, but a potential for causing serious …

Effect of steroid pulses in severe BK virus allograft nephropathy with extensive interstitial inflammation

J Carrillo, A Del Bello, F Sallusto… - Transplant Infectious …, 2024 - Wiley Online Library
Introduction As there is no specific antiviral treatment currently available for BK polyomavirus
associated nephropathy (BKVAN), its management relies on immunosuppression reduction …