Malaria remains a major cause of morbidity and mortality in the tropics, with Plasmodium
falciparum responsible for the majority of the disease burden and P. vivax being the …

Background The burden of malaria infection in sub-Saharan Africa among school-aged
children aged 5–15 years is underappreciated and represents an important source of …

Malaria cases and deaths remain unacceptably high and are resurgent in several settings,
though recent developments inspire optimism. This includes the approval of the world's first …

Background Haemoglobinopathies can reduce the risk of malaria syndromes. We aimed to
quantify the relation between different haemoglobin mutations and malaria protection to …

Background The control and elimination of malaria requires expanded coverage of and
access to effective malaria control interventions such as insecticide-treated nets (ITNs) …

Background We have shown that immunity to infection with Plasmodium falciparum can be
induced experimentally in malaria-naive volunteers through immunisation by bites of …

Despite being one of the most prevalent tropical diseases, for many years malaria was not a
commercial priority for the pharmaceutical industry. However, in response to the emergence …

Background Seasonal Malaria Chemoprevention (SMC) with sulfadoxine-pyrimethamine
(SP) plus amodiaquine (AQ), given each month during the transmission season, is …

The past decade witnessed unprecedented efforts to control malaria, including renewed
political and financial commitment and increased availability of both old and new strategies …

BACkground Plasmodium resistance to antimalarial medicines is one of the major obstacles
in the fight against malaria. Comprehensive, up-to-date understanding of the scope of …