Dual TCR T cells are a common and natural product of TCR gene rearrangement and
thymocyte development. As much as one third of the T cell population may have the …

T cell recognition of antigen is a crucial aspect of the adaptive immune response. One of the
most common means of pathogen immune evasion is mutation of T cell epitopes. T cell …

Immunity to influenza is unique among pathogens, in that immune memory is established
both via intermittent lung localized infections with highly variable influenza virus strains and …

Changes in the peptide and MHC molecules have been extensively examined for how they
alter T cell activation, but many fewer studies have examined the TCR. Structural studies of …

The culmination of 30 years of research and experience in T-cell-based cancer, this book
highlights and evaluates new treatments that harness the power of the T cell to attack and …

Cancer is one of the most difficult health problems our society faces. Cancer research is a
multi-billion dollar endeavor that encompasses the intellectual efforts of scientists around the …

Abstract< i> Mycobacterium tuberculosis</i>(Mtb) is an intracellular pathogen that infects
lung macrophages. On macrophages and T cells, Mtb lipoproteins and lipoglycans regulate …

The T cell is a critical player in the adaptive immune response. T cells function by stimulating
antibody production by B cells, secreting cytokines to attract other immune cells, regulating …

The outcomes of T cell interaction with antigen are determined by a complex integration of
positive and negative signaling events downstream of the T cell receptor. The introduction of …