[HTML][HTML] NIA-AA research framework: toward a biological definition of Alzheimer's disease
CR Jack Jr, DA Bennett, K Blennow, MC Carrillo… - Alzheimer's & …, 2018 - Elsevier
Abstract In 2011, the National Institute on Aging and Alzheimer's Association created
separate diagnostic recommendations for the preclinical, mild cognitive impairment, and …
separate diagnostic recommendations for the preclinical, mild cognitive impairment, and …
In vivo tau PET imaging in dementia: pathophysiology, radiotracer quantification, and a systematic review of clinical findings
In addition to the deposition of β-amyloid plaques, neurofibrillary tangles composed of
aggregated hyperphosphorylated tau are one of the pathological hallmarks of Alzheimer's …
aggregated hyperphosphorylated tau are one of the pathological hallmarks of Alzheimer's …
Differential levels of plasma biomarkers of neurodegeneration in Lewy body dementia, Alzheimer's disease, frontotemporal dementia and progressive supranuclear …
Objectives This longitudinal study compared emerging plasma biomarkers for
neurodegenerative disease between controls, patients with Alzheimer's disease (AD), Lewy …
neurodegenerative disease between controls, patients with Alzheimer's disease (AD), Lewy …
Myocardial inflammation predicts remodeling and neuroinflammation after myocardial infarction
JT Thackeray, HC Hupe, Y Wang, JP Bankstahl… - Journal of the American …, 2018 - jacc.org
Background: The local inflammatory tissue response after acute myocardial infarction (MI)
determines subsequent healing. Systemic interaction may induce neuroinflammation as a …
determines subsequent healing. Systemic interaction may induce neuroinflammation as a …
Neuroinflammation and functional connectivity in Alzheimer's disease: interactive influences on cognitive performance
L Passamonti, KA Tsvetanov, PS Jones… - Journal of …, 2019 - Soc Neuroscience
Neuroinflammation is a key part of the etio-pathogenesis of Alzheimer's disease (AD). We
tested the relationship between neuroinflammation and the disruption of functional …
tested the relationship between neuroinflammation and the disruption of functional …
Microglial activation and tau burden predict cognitive decline in Alzheimer's disease
Tau pathology, neuroinflammation, and neurodegeneration are key aspects of Alzheimer's
disease. Understanding whether these features predict cognitive decline, alone or in …
disease. Understanding whether these features predict cognitive decline, alone or in …
Tau burden and the functional connectome in Alzheimer's disease and progressive supranuclear palsy
Alzheimer's disease and progressive supranuclear palsy (PSP) represent
neurodegenerative tauopathies with predominantly cortical versus subcortical disease …
neurodegenerative tauopathies with predominantly cortical versus subcortical disease …
18F-AV-1451 positron emission tomography in Alzheimer's disease and progressive supranuclear palsy
The ability to assess the distribution and extent of tau pathology in Alzheimer's disease and
progressive supranuclear palsy in vivo would help to develop biomarkers for these …
progressive supranuclear palsy in vivo would help to develop biomarkers for these …
Microglial activation in the frontal cortex predicts cognitive decline in frontotemporal dementia
M Malpetti, TE Cope, D Street, PS Jones… - Brain, 2023 - academic.oup.com
Frontotemporal dementia is clinically and neuropathologically heterogeneous, but
neuroinflammation, atrophy and cognitive impairment occur in all of its principal syndromes …
neuroinflammation, atrophy and cognitive impairment occur in all of its principal syndromes …
Neuroinflammation and protein aggregation co-localize across the frontotemporal dementia spectrum
The clinical syndromes of frontotemporal dementia are clinically and neuropathologically
heterogeneous, but processes such as neuroinflammation may be common across the …
heterogeneous, but processes such as neuroinflammation may be common across the …