The function of the nervous system depends on the exocytotic release of neurotransmitter
from synaptic vesicles (SVs). To sustain neurotransmission, SV membranes need to be …

Neurotransmission in complex animals depends on a choir of functionally distinct synapses
releasing neurotransmitters in a highly coordinated manner. During synaptic signaling …

The protein α-synuclein has a central role in the pathogenesis of Parkinson's disease. Like
that of other proteins that accumulate in neurodegenerative disease, however, the function …

Fusion is thought to open a pore to release vesicular cargoes vital for many biological
processes, including exocytosis, intracellular trafficking, fertilization, and viral entry …

Vesicle fusion is executed via formation of an Ω-shaped structure (Ω-profile), followed by
closure (kiss-and-run) or merging of the Ω-profile into the plasma membrane (full fusion) …

Dynamin superfamily proteins (DSPs) mediate membrane fission and fusion necessary for
endocytosis, organelle biogenesis and maintenance, as well as for bacterial cytokinesis …

Membrane fusion and fission are vital for eukaryotic life,,,,. For three decades, it has been
proposed that fusion is mediated by fusion between the proximal leaflets of two bilayers …

Many cellular activities, such as cell migration, cell division, phagocytosis, and exo-
endocytosis, generate and are regulated by membrane tension gradients. Membrane …

Transformation of flat membrane into round vesicles is generally thought to underlie
endocytosis and produce speed-, amount-, and vesicle-size-specific endocytic modes …

How structural and functional properties of synapses relate to each other is a fundamental
question in neuroscience. Electrophysiology has elucidated mechanisms of synaptic …