Objective Use of the frailty index to measure an accumulation of deficits has been proven a
valuable method for identifying elderly people at risk for increased vulnerability, disease …

Human biology follows recurring daily rhythms that are governed by circadian cues in the
environment. Here we show that human milk is a powerful form of “chrononutrition,” …

Despite the high prevalence of acute kidney injury (AKI), the therapeutic approaches for AKI
are disappointing. This deficiency stems from the poor understanding of the pathogenesis of …

Early overnutrition disrupts leptin sensitivity and the development of hypothalamic pathways
involved in the regulation of metabolism and feeding behavior. While previous studies have …

Aim: The aim of this study is to identify a gene prognostic signature for the head-and-neck
squamous cell carcinoma (HNSCC). HNSCC is one of the most common malignancies …

This study aimed to investigate the role of leptin, ghrelin, neuropeptide Y, and nesfatin-1 in
young children with autism spectrum disorder (ASD). A total of 44 children with ASD and 44 …

Circadian disruptions precede high-fat diet (HFD)-induced obesity (DIO). Deviation of the
endogenous circadian rhythm period length (tau) from 24 hours correlates with mice inter …

Perturbations in postnatal leptin signaling have been associated with altered susceptibility to
diet-induced obesity (DIO) under high-fat-diet (HFD), albeit with contradicting evidence …

* Corresponding author: Roee Gutman, Laboratory of Integrative Physiology (LIP). MIGAL-
18 Galilee Research Institute. POB 831, Kiryat Shmona, 11016, Israel. Tel: 972-4-6953569 …