Insights into the structure activity relationship of nitrogen-containing heterocyclics for the development of antidepressant compounds: An updated review

K Singh, R Pal, SA Khan, B Kumar, MJ Akhtar - Journal of Molecular …, 2021 - Elsevier
Abstract According to the World Health Organization (WHO), depression is a common
mental disorder and includes complex interaction between social and psychological …

[HTML][HTML] A Review on Benzimidazole Heterocyclic Compounds: Synthesis and Their Medicinal Activity Applications

LA Mohammed, MA Farhan, SA Dadoosh… - …, 2023 - thieme-connect.com
Benzimidazole is a heterocyclic compound that contains two nitrogen atoms and is formed
by fusing a benzene ring with an imidazole. Benzimidazole and its derivatives are prepared …

[PDF][PDF] Synthesis, SC XRD Based Structure Elucidation, Supramolecular Assembly Exploration Via Hirshfeld Surface Analysis, Computational and QTAIM Study of …

MN Tahir, M Ashfaq, A Ali, CH Lai, BR Rao… - Acta Chimica …, 2023 - researchgate.net
The anilide compound named (Z)-4-(2-methoxy-4-nitrophenyl) amino)-4-oxobut-2-enoic
acid (MAOA) has been synthesized by the chemical reaction of 2-methoxy-4-nitroaniline and …

Crystal structure, supramolecular assembly exploration by Hirshfeld surface analysis and DFT inspection of the synthesized functionalized crystalline anilide

M Ashfaq, MN Tahir, G Bogdanov, A Ali… - Journal of the Iranian …, 2023 - Springer
The current research work is about the synthesis of functionalized crystalline anilide, ie,(Z)-4-
((2-nitrophenyl) amino)-4-oxobut-2-enoic acid (NAOB) and its experimental and theoretical …

CO-releasing, antioxidant, antibacterial, zeta potential, theoretical, and electrochemical analysis of [Mn (CO) 3 (bpy) L] OTf type complexes

E Üstün, D Şakar, MÇ Ayvaz, MS Çelebi, Ö Ertürk - Polyhedron, 2022 - Elsevier
In pharmaceutical chemistry, both N-heterocyclic compounds and metal carbonyl complexes
are well-known families because their several bioactivities. N-heterocyclics have been used …

Design, graph theoretical analysis and in silico modeling of Dunaliella bardawil biomass encapsulated keratin nanoparticles: a scaffold for effective glucose utilization

S Kunjiappan, T Panneerselvam, P Prasad… - Biomedical …, 2018 - iopscience.iop.org
The aim of the present study is to develop keratin nanoparticles (NPs) encapsulated in
Dunaliella bardawil (D. bardawil) biomass, in order to improve their glucose uptake in 3T3 …

Graph theoretical analysis, in silico modeling, synthesis, anti-microbial and anti-TB evaluation of novel quinoxaline derivatives

G Saravanan, TP Selvam, V Alagarsamy… - Drug …, 2018 - thieme-connect.com
Background We designed to synthesize a number of 2-(2-(substituted benzylidene)
hydrazinyl)-N-(4-((3-(phenyl imino)-3, 4-dihydro quinoxalin-2 (1 H)-ylidene) amino) phenyl) …

In silico pharmacology

S Pathak, A Mishra, G Sonawane, K Sonawane… - … Approaches in Drug …, 2023 - Elsevier
It has been a primary focus over the last 50 years to develop computational approaches for
predicting the various pharmacodynamic (PD) and pharmacokinetic (PK) characteristics that …

Synthesis of isoxazolylpyrrolones by three-component reaction of α-ketoglutaric acid or its diethyl ester with 3-amino-5-methylisoxazole and aromatic aldehydes

YI Sakhno, OV Radchenko, EA Muravyova… - Chemistry of …, 2021 - Springer
Synthesis of isoxazolylpyrrolones by three-component reaction of α-ketoglutaric acid or its
diethyl ester with 3-amino-5-methylisoxazole and aromatic aldehydes | Chemistry of …

Design, Optimization, Synthesis and AntiTB Screening of Benzimidazole Derivatives

T Panneerselvam, S Kunjiappan… - Anti-Infective …, 2020 - ingentaconnect.com
Introduction: A biologically active benzimidazole synthesis was carried out at laboratory
scale in order to reduce environmental pollution as well as to identify effective synthetic …