Taurine is an organic osmolyte involved in cell volume regulation, and provides a substrate
for the formation of bile salts. It plays a role in the modulation of intracellular free calcium …

Retinal neurodegenerative diseases like age-related macular degeneration, glaucoma,
diabetic retinopathy and retinitis pigmentosa each have a different etiology and …

Hereditary degenerations of the human retina are genetically heterogeneous, with well over
100 genes implicated so far. This Seminar focuses on the subset of diseases called retinitis …

Objective To review and synthesize information concerning the pathogenesis ofage-related
macular degeneration (AMD). Methods Review of the English-language literature. Results …

Macular telangiectasia type 2 is a bilateral disease of unknown cause with characteristic
alterations of the macular capillary network and neurosensory atrophy. Its prevalence may …

Dr. Jacqueline N. Crawley, author of the First and Second Editions of What's Wrong with My
Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice, continues to field calls …

In the developing vertebrate retina, diverse neuronal subtypes originate from multipotent
progenitors in a conserved order and are integrated into an intricate laminated architecture …

By its action on rhodopsin, light triggers the well-known visual transduction cascade, but can
also induce cell damage and death through phototoxic mechanisms–a comprehensive …

purpose. To determine whether acute experimental glaucoma in rats obstructs retrograde
transport of brain-derived neurotrophic factor (BDNF) to retinal ganglion cells (RGCs) …

Blindness affects 60 million people worldwide. The leading causes of irreversible blindness
include age-related macular degeneration, retinal vascular diseases and glaucoma. The …