Cancer of the Liver and its Relationship with Diabetes mellitus

SA Onikanni, B Lawal, OS Bakare… - … in Cancer Research …, 2022 - journals.sagepub.com
A high increase witnessed in type II diabetes mellitus (T2DM) globally has increasingly
posed a serious threat to global increases in liver cancer with the association between …

[HTML][HTML] Therapeutic efficacy of Clompanus pubescens leaves fractions via downregulation of neuronal cholinesterases/Na+-K+ ATPase/IL-1 β, and improving the …

AS Onikanni, B Lawal, BE Oyinloye… - Biomedicine & …, 2022 - Elsevier
The increasing global burden of diabetes mellitus has called for the search for a therapeutic
alternative that offers better activities and safety than conventional chemotherapy. Herein …

[HTML][HTML] Preclinical anti-inflammatory and antioxidant effects of Azanza garckeana in STZ-induced glycemic-impaired rats, and pharmacoinformatics of it major …

B Lawal, S Sani, AS Onikanni, YO Ibrahim… - Biomedicine & …, 2022 - Elsevier
The quest for novel anti-diabetic medication from medicinal plants is very important since
they contain bioactive phytochemicals that offer better activity and safety compared to …

Luteolin‐Rich Extract of Thespesia garckeana F. Hoffm. (Snot Apple) Contains Potential Drug‐Like Candidates and Modulates Glycemic and Oxidoinflammatory …

UB Alozieuwa, B Lawal, S Sani… - Oxidative Medicine …, 2022 - Wiley Online Library
The present study evaluated the polyphenolic contents and hypoglycemic, antioxidant, and
anti‐inflammatory effects of the diethyl ether fraction of Thespesia garckeana using various …

Sterculia tragacantha Lindl Leaf Extract Ameliorates STZ-Induced Diabetes, Oxidative Stress, Inflammation and Neuronal Impairment

AS Onikanni, B Lawal, AO Olusola… - Journal of …, 2021 - Taylor & Francis
Background Sterculia tragacantha is a medicinal plant commonly used in the western part of
Nigeria, for managing diabetes mellitus. However, there is a dearth of scientific information …

Transcriptomic-based identification of the immuno-oncogenic signature of cholangiocarcinoma for HLC-018 multi-target therapy exploration

B Lawal, YC Kuo, SL Tang, FC Liu, ATH Wu, HY Lin… - Cells, 2021 - mdpi.com
Cholangiocarcinomas (CHOLs), hepatobiliary malignancies, are characterized by high
genetic heterogeneity, a rich tumor microenvironment, therapeutic resistance, difficulty …

Multiomics identification of potential targets for Alzheimer disease and antrocin as a therapeutic candidate

ATH Wu, B Lawal, L Wei, YT Wen, DTW Tzeng, WC Lo - Pharmaceutics, 2021 - mdpi.com
Alzheimer's disease (AD) is the most frequent cause of neurodegenerative dementia and
affects nearly 50 million people worldwide. Early stage diagnosis of AD is challenging, and …

In vivo pharmacokinetic and anticancer studies of HH-N25, a selective inhibitor of topoisomerase I, and hormonal signaling for treating breast cancer

B Lawal, YC Kuo, MR Sumitra, ATH Wu… - Journal of …, 2021 - Taylor & Francis
Purpose Breast cancer is the most frequently diagnosed cancer globally, and the leading
cause of cancer-associated mortality among women. The efficacy of most clinical …

[HTML][HTML] Attenuation of hyperglycemia-associated dyslipidemic, oxidative, cognitive, and inflammatory crises via modulation of neuronal ChEs/NF-κB/COX-2/NOx, and …

IA Hogan, YC Kuo, AN Abubakar, B Lawal… - Biomedicine & …, 2023 - Elsevier
Tridax procumbens (cotton buttons) is a flowering plant with a medicinal reputation for
treating infections, wounds, diabetes, and liver and kidney diseases. The present research …

Identification of NSP3 (SH2D3C) as a prognostic biomarker of tumor progression and immune evasion for lung cancer and evaluation of organosulfur compounds from …

YC Yeh, B Lawal, M Hsiao, TH Huang, CYF Huang - Biomedicines, 2021 - mdpi.com
The multi-domain non-structural protein 3 (NSP3) is an oncogenic molecule that has been
concomitantly implicated in the progression of coronavirus infection. However, its …