Management of fever in patients with cancer and treatment-induced neutropenia

PA Pizzo - New England Journal of Medicine, 1993 - Mass Medical Soc
The importance of neutropenia in the risk of serious infection in patients with cancer who are
receiving cytotoxic chemotherapy was first recognized nearly 30 years ago1. Since then …

The biology and clinical uses of blood stem cells

LB To, DN Haylock, PJ Simmons… - Blood, The Journal of …, 1997 - ashpublications.org
''It seems more than ever likely that blood-derived stem tive capacity. 47-49 In the allogeneic
setting, mobilized blood cells have also been used instead of BM. 50 Umbilical cord cells …

Effect of peripheral-blood progenitor cells mobilised by filgrastim (G-CSF) on platelet recovery after high-dose chemotherapy

WP Sheridan, RM Fox, CG Begley, D Maher… - The Lancet, 1992 - Elsevier
The haemopoietic growth factor granulocyte colony-stimulating factor (G-CSF; filgrastim)
substantially shortens the period of severe neutropenia that follows high-dose …

[HTML][HTML] Poor mobilization of hematopoietic stem cells—definitions, incidence, risk factors, and impact on outcome of autologous transplantation

P Wuchter, D Ran, T Bruckner, T Schmitt… - Biology of Blood and …, 2010 - Elsevier
As more efficient agents for stem cell mobilization are being developed, there is an urgent
need to define which patient population might benefit from these novel drugs. For a precise …

Peripheral blood stem cell transplants for multiple myeloma: identification of favorable variables for rapid engraftment in 225 patients

G Tricot, S Jagannath, D Vesole, J Nelson, S Tindle… - 1995 - ashpublications.org
Transfusion of autologous peripheral blood stem cells (PBSCs) of good quality ensures fast
hematopoietic engraftment after myeloablative therapy with a decrease in procedure-related …

Therapeutic relevance of CD34 cell dose in blood cell transplantation for cancer therapy

S Siena, R Schiavo, P Pedrazzoli… - Journal of Clinical …, 2000 - ascopubs.org
PURPOSE: To review recent advances in peripheral-blood progenitor-cell (PBPC)
transplantation in order to define the optimal cell dose required for autologous and …

Ex vivo expansion of enriched peripheral blood CD34+ progenitor cells by stem cell factor, interleukin-1 beta (IL-1 beta), IL-6, IL-3, interferon-gamma, and …

W Brugger, W MOcklin, S Heimfeld, RJ Berenson… - 1993 - ashpublications.org
To provide sufficient numbers of peripheral blood progenitor cells (PBPCs) for repetitive use
after high-dose chemotherapy, we investigated the ability of hematopoietic growth factor …

The colony-stimulating factors and cancer

D Metcalf - Nature Reviews Cancer, 2010 - nature.com
The four colony-stimulating factors (CSFs) are glycoproteins that regulate the generation
and some functions of infection-protective granulocytes and macrophages. Recombinant …

Autologous transplantation with peripheral blood mononuclear cells collected after administration of recombinant granulocyte stimulating factor

W Bensinger, J Singer, F Appelbaum, K Lilleby… - 1993 - ashpublications.org
Peripheral blood mononuclear cells (PBMC) were collected after the administration of
recombinant human granulocyte colony-stimulating factor (rhG-CSF) and used as the sole …

Peripheral blood stem cells (PBSCs) collected after recombinant granulocyte colony stimulating factor (rhG‐CSF): an analysis of factors correlating with the tempo of …

WI Bensinger, K Longin, F Appelbaum… - British journal of …, 1994 - Wiley Online Library
Factors affecting mobilization and engraftment were analysed in 54 patients undergoing
transplant using autologous PBSCs mobilized with high‐dose recombinant granulocyte …