Advances in the measurement of red blood cell deformability: A brief review

J Kim, HY Lee, S Shin - Journal of Cellular Biotechnology, 2015 - content.iospress.com
Red blood cells (RBCs) exhibit a unique deformability, which enables them to change shape
reversibly in response to an external force. The deformability of RBCs allows them to flow in …

Technologies for measuring red blood cell deformability

K Matthews, ES Lamoureux, ME Myrand-Lapierre… - Lab on a Chip, 2022 - pubs.rsc.org
Human red blood cells (RBCs) are approximately 8 μm in diameter, but must repeatedly
deform through capillaries as small as 2 μm in order to deliver oxygen to all parts of the …

Assessment of red blood cell deformability in type 2 diabetes mellitus and diabetic retinopathy by dual optical tweezers stretching technique

R Agrawal, T Smart, J Nobre-Cardoso, C Richards… - Scientific reports, 2016 - nature.com
A pilot cross sectional study was conducted to investigate the role of red blood cells (RBC)
deformability in type 2 diabetes mellitus (T2DM) without and with diabetic retinopathy (DR) …

Deformation of red blood cells, air bubbles, and droplets in microfluidic devices: Flow visualizations and measurements

D Bento, RO Rodrigues, V Faustino, D Pinho… - Micromachines, 2018 - mdpi.com
Techniques, such as micropipette aspiration and optical tweezers, are widely used to
measure cell mechanical properties, but are generally labor-intensive and time-consuming …

A microfluidic deformability assessment of pathological red blood cells flowing in a hyperbolic converging microchannel

V Faustino, RO Rodrigues, D Pinho, E Costa… - Micromachines, 2019 - mdpi.com
The loss of the red blood cells (RBCs) deformability is related with many human diseases,
such as malaria, hereditary spherocytosis, sickle cell disease, or renal diseases. Hence …

Changes in erythrocyte aggregation and deformability in diabetes mellitus: a brief review

M Singh, S Shin - 2009 - nopr.niscpr.res.in
Diabetes mellitus (DM) is a metabolic disorder characterized by varying or persistent
hyperglycemia either due to insufficient production of insulin by pancreas or improper …

[HTML][HTML] Abnormal urinary loss of vitamin C in diabetes: prevalence and clinical characteristics of a vitamin C renal leak

I Ebenuwa, PC Violet, S Padayatty, Y Wang… - The American Journal of …, 2022 - Elsevier
Background Diabetes is associated with low plasma vitamin C concentrations. Objectives
We investigated the contribution of dysregulated vitamin C renal physiology, its prevalence …

Toxic effects of silver nanoparticles and nanowires on erythrocyte rheology

MJ Kim, S Shin - Food and chemical toxicology, 2014 - Elsevier
Rapid developments in the food applications of silver nanomaterials (Ag-NMs) have resulted
in concerns related to the risk of overexposure of human blood. We investigated the effect of …

Human red blood cell behavior under homogeneous extensional flow in a hyperbolic-shaped microchannel

T Yaginuma, MSN Oliveira, R Lima, T Ishikawa… - …, 2013 - pubs.aip.org
It is well known that certain pathological conditions result in a decrease of red blood cells
(RBCs) deformability and subsequently can significantly alter the blood flow in …

The influence of red blood cell deformability on hematocrit profiles and platelet margination

B Czaja, M Gutierrez, G Závodszky… - PLOS Computational …, 2020 - journals.plos.org
The influence of red blood cell (RBC) deformability in whole blood on platelet margination is
investigated using confocal microscopy measurements of flowing human blood and cell …