The complex pathophysiology of autism spectrum disorder encompasses interactions
between genetic and environmental factors. On the one hand, hundreds of genes …

The recent epidemics of metabolic diseases, obesity, type 2 diabetes (T2D), liver lipid
disorders and metabolic syndrome have largely been attributed to genetic background and …

Abstract The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …

Microplastics (MPs) are considered as a pollutant of marine environments and have become
a global environmental problem in recent years. A number of studies have demonstrated …

Developmental origins of health and disease (DOHaD) is the study of how the early life
environment can impact the risk of chronic diseases from childhood to adulthood and the …

The increasing incidence of obesity is a serious global public health challenge. Although the
obesity epidemic is largely fueled by poor nutrition and lack of exercise, certain chemicals …

Benzene, toluene, ethylbenzene, and xylene (BTEX) are retrieved during fossil fuel
extraction and used as solvents in consumer and industrial products, as gasoline additives …

There are now robust data supporting the Developmental Origins of Health and Disease
(DOHaD) paradigm. This includes human and animal data focusing on nutrition or …

The fact that not all individuals exposed to the same environmental risk factors develop
obesity supports the hypothesis of the existence of underlying genetic and epigenetic …

The evidence in support of the developmental origins of the health and disease paradigm is
sufficiently robust and repeatable across species, including humans, to suggest a need for …