The development of femtosecond lasers brought entirely new possibilities into the practice of
timeresolved spectroscopy, for both UV-vis and IR-Raman spectroscopies. In addition, it has …

This tutorial review gathers together the recent developments in single-crystal X-ray
diffraction that are starting to enable one to quantify directly the nature of light-induced …

Small molecules such as NO, O2, CO or H2 are important biological ligands that bind to
metalloproteins to function crucially in processes such as signal transduction, respiration …

MYOGLOBIN is a globular haem protein that reversibly binds lig-ands such as O2 and CO.
Single photons of visible light can break the covalent bond between CO and the haem iron …

The first quantitative analyses are reported of the Fe K-edge polarized X-ray absorption near-
edge structure (XANES) of a single crystal of the iron protein carbonmonoxy-myoglobin …

We present the extension of time-resolved optical pump/x-ray absorption spectroscopy
(XAS) probe experiments towards data collection at MHz repetition rates. The use of a high …

Myoglobin's reversible binding of oxygen is a model for studies of protein control of ligand
binding and discrimination. Protein relaxation and geminate ligand rebinding subsequent to …

The x-ray structure of carbon monoxide (CO)-ligated myoglobin illuminated during data
collection by a laser diode at the wavelength lambda= 690 nm has been determined to a …

Using Fourier transform infrared (FTIR) spectroscopy combined with temperature derivative
spectroscopy (TDS) at cryogenic temperatures, we have studied CO binding to the heme …

First published in 1990, this comprehensive monograph consists of two parts: Volume I,
entitled Enzyme Catalysis, Kinetics, and Substrate Binding; and Volume II, entitled …