Extracellular vesicles (EVs) are membrane enclosed micro-and nano-sized vesicles that are secreted from almost every species, ranging from prokaryotes to eukaryotes, and from …
Single-cell RNA sequencing has enabled the decomposition of complex tissues into functionally distinct cell types. Often, investigators wish to assign cells to cell types through …
Exosomes show potential for cancer diagnostics because they transport molecular contents of the cells from which they originate. Detection and molecular profiling of exosomes is …
Extracellular vesicles, including exosomes, are nanoscale membrane particles that carry molecular information on parental cells. They are being pursued as biomarkers of cancers …
Tumor-derived circulating exosomes, enriched with a group of tumor antigens, have been recognized as a promising biomarker source for cancer diagnosis via a less invasive …
TKW Lee, A Castilho, VCH Cheung, KH Tang, S Ma… - Cell stem cell, 2011 - cell.com
Tumor-initiating cells (T-ICs) are a subpopulation of chemoresistant tumor cells that have been shown to cause tumor recurrence upon chemotherapy. Identification of T-ICs and their …
W Zhao, Y Li, X Zhang - Cancer translational medicine, 2017 - ncbi.nlm.nih.gov
Cancer stem cells (CSCs), with their self-renewal ability and multilineage differentiation potential, are a critical subpopulation of tumor cells that can drive tumor initiation, growth …
SS Yin, FH Gao - Frontiers in immunology, 2020 - frontiersin.org
Tumor immune escape is an important part of tumorigenesis and development. Tumor cells can develop a variety of immunosuppressive mechanisms to combat tumor immunity …
MQ Gao, YP Choi, S Kang, JH Youn, NH Cho - Oncogene, 2010 - nature.com
Cancer stem cells (CSCs) have been identified in solid tumors and cancer cell lines. In this study, we isolated a series of cancer cell clones, which were heterogeneous in growth rate …