[HTML][HTML] Targeting tumor-associated macrophages for successful immunotherapy of ovarian carcinoma

I Truxova, D Cibula, R Spisek… - … for immunotherapy of …, 2023 - ncbi.nlm.nih.gov
Epithelial ovarian cancer (EOC) is among the top five causes of cancer-related death in
women, largely reflecting early, prediagnosis dissemination of malignant cells to the …

Extracellular vesicles and matrix remodeling enzymes: the emerging roles in extracellular matrix remodeling, progression of diseases and tissue repair

M Nawaz, N Shah, BR Zanetti, M Maugeri, RN Silvestre… - Cells, 2018 - mdpi.com
Extracellular vesicles (EVs) are membrane enclosed micro-and nano-sized vesicles that are
secreted from almost every species, ranging from prokaryotes to eukaryotes, and from …

Probabilistic cell-type assignment of single-cell RNA-seq for tumor microenvironment profiling

AW Zhang, C O'Flanagan, EA Chavez, JLP Lim… - Nature …, 2019 - nature.com
Single-cell RNA sequencing has enabled the decomposition of complex tissues into
functionally distinct cell types. Often, investigators wish to assign cells to cell types through …

Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor

H Im, H Shao, YI Park, VM Peterson, CM Castro… - Nature …, 2014 - nature.com
Exosomes show potential for cancer diagnostics because they transport molecular contents
of the cells from which they originate. Detection and molecular profiling of exosomes is …

Integrated magneto–electrochemical sensor for exosome analysis

S Jeong, J Park, D Pathania, CM Castro… - ACS …, 2016 - ACS Publications
Extracellular vesicles, including exosomes, are nanoscale membrane particles that carry
molecular information on parental cells. They are being pursued as biomarkers of cancers …

A microfluidic ExoSearch chip for multiplexed exosome detection towards blood-based ovarian cancer diagnosis

Z Zhao, Y Yang, Y Zeng, M He - Lab on a Chip, 2016 - pubs.rsc.org
Tumor-derived circulating exosomes, enriched with a group of tumor antigens, have been
recognized as a promising biomarker source for cancer diagnosis via a less invasive …

[HTML][HTML] CD24+ liver tumor-initiating cells drive self-renewal and tumor initiation through STAT3-mediated NANOG regulation

TKW Lee, A Castilho, VCH Cheung, KH Tang, S Ma… - Cell stem cell, 2011 - cell.com
Tumor-initiating cells (T-ICs) are a subpopulation of chemoresistant tumor cells that have
been shown to cause tumor recurrence upon chemotherapy. Identification of T-ICs and their …

[HTML][HTML] Stemness-related markers in cancer

W Zhao, Y Li, X Zhang - Cancer translational medicine, 2017 - ncbi.nlm.nih.gov
Cancer stem cells (CSCs), with their self-renewal ability and multilineage differentiation
potential, are a critical subpopulation of tumor cells that can drive tumor initiation, growth …

Molecular mechanism of tumor cell immune escape mediated by CD24/Siglec-10

SS Yin, FH Gao - Frontiers in immunology, 2020 - frontiersin.org
Tumor immune escape is an important part of tumorigenesis and development. Tumor cells
can develop a variety of immunosuppressive mechanisms to combat tumor immunity …

CD24+ cells from hierarchically organized ovarian cancer are enriched in cancer stem cells

MQ Gao, YP Choi, S Kang, JH Youn, NH Cho - Oncogene, 2010 - nature.com
Cancer stem cells (CSCs) have been identified in solid tumors and cancer cell lines. In this
study, we isolated a series of cancer cell clones, which were heterogeneous in growth rate …