Antimicrobial peptides and proteins: From nature's reservoir to the laboratory and beyond

T Sarkar, M Chetia, S Chatterjee - Frontiers in Chemistry, 2021 - frontiersin.org
Rapid rise of antimicrobial resistance against conventional antimicrobials, resurgence of
multidrug resistant microbes and the slowdown in the development of new classes of …

[HTML][HTML] Antimicrobial peptides with selective antitumor mechanisms: prospect for anticancer applications

B Deslouches, YP Di - Oncotarget, 2017 - ncbi.nlm.nih.gov
In the last several decades, there have been significant advances in anticancer therapy.
However, the development of resistance to cancer drugs and the lack of specificity related to …

Antimicrobial and antibiofilm peptides

A Di Somma, A Moretta, C Canè, A Cirillo, A Duilio - Biomolecules, 2020 - mdpi.com
The increasing onset of multidrug-resistant bacteria has propelled microbiology research
towards antimicrobial peptides as new possible antibiotics from natural sources …

The chemistry and biological activities of peptides from amphibian skin secretions

X Xu, R Lai - Chemical reviews, 2015 - ACS Publications
Amphibian skin is directly exposed to different environments. Amphibians interact with
environmental factors including microorganisms, parasites, predators, and physical factors …

Emerging knowledge of regulatory roles of d-amino acids in bacteria

F Cava, H Lam, MA De Pedro, MK Waldor - Cellular and Molecular Life …, 2011 - Springer
The d-enantiomers of amino acids have been thought to have relatively minor functions in
biological processes. While l-amino acids clearly predominate in nature, d-amino acids are …

Emerging trends in macromolecular antimicrobials to fight multi-drug-resistant infections

AC Engler, N Wiradharma, ZY Ong, DJ Coady… - Nano Today, 2012 - Elsevier
Synthetic macromolecular antimicrobials are a highly promising class of therapeutics with
immense potential for combating multidrug resistant microbes. In contrast to conventional …

Designing improved active peptides for therapeutic approaches against infectious diseases

B Gomes, MT Augusto, MR Felício, A Hollmann… - Biotechnology …, 2018 - Elsevier
Infectious diseases are one of the main causes of human morbidity and mortality. In the last
few decades, pathogenic microorganisms' resistance to conventional drugs has been …

Strategies in translating the therapeutic potentials of host defense peptides

DSJ Ting, RW Beuerman, HS Dua… - Frontiers in …, 2020 - frontiersin.org
The golden era of antibiotics, heralded by the discovery of penicillin, has long been
challenged by the emergence of antimicrobial resistance (AMR). Host defense peptides …

Origin, Microbiology, Nutrition, and Pharmacology of D‐Amino Acids

M Friedman - Chemistry & biodiversity, 2010 - Wiley Online Library
Exposure of food proteins to certain processing conditions induces two major chemical
changes: racemization of all l‐amino acids (LAAs) to d‐amino acids (DAAs) and concurrent …

Antimicrobial peptides: amphibian host defense peptides

J Patocka, E Nepovimova, B Klimova… - Current medicinal …, 2019 - ingentaconnect.com
Antimicrobial Peptides (AMPs) are one of the most common components of the innate
immune system that protect multicellular organisms against microbial invasion. The vast …