Intracellular pathogens have evolved various efficient molecular armaments to subvert
innate defenses. Cellular ubiquitination, a normal physiological process to maintain …

Kaempferol, a flavonoid, found in traditional medicine, fruits, and vegetables, and an HDAC
inhibitor, is a powerful anti-cancer reagent against various cancer cell lines. However …

Growing evidence implicates histone H3 lysine 9 methylation in tumorigenesis. The SUV
family of H3K9 methyltransferases, which include G9a, GLP, SETDB1, SETDB2, SUV39H1 …

Bladder cancer is lethal in its advanced, muscle-invasive phase with very limited therapeutic
advances,. Recent molecular characterization has defined new (epi) genetic drivers and …

Previous reports suggested that cinnamaldehyde (CA), the bioactive ingredient in
Cinnamomum cassia, can suppress tumor growth, migratory, and invasive abilities …

Behavioural and psychological symptoms of dementia (BPSD) are presented in 95% of
Alzheimer's Disease (AD) patients and are also associated with neurotrophin deficits. The …

Background Metformin has been reported to function as the anti-tumor inhibiting the growth
of different types of cancers, including bladder cancer. But there are few reports on the roles …

Urinary bladder cancer (UBC) is characterized by frequent recurrence and metastasis
despite the standard chemotherapy with gemcitabine and cisplatin combination. Histone …

Ewing sarcoma (EWS) is an aggressive bone and soft tissue tumor with high susceptibility to
metastasize. The underlying molecular mechanisms leading to EWS metastases remain …

Euchromatic histone lysine methyltransferase-2, also known as G9a, is a ubiquitously
expressed SET domain-containing histone lysine methyltransferase linked with both …