Conventional and emerging strategies for the fabrication and functionalization of PDMS-based microfluidic devices

A Shakeri, S Khan, TF Didar - Lab on a Chip, 2021 - pubs.rsc.org
Microfluidics is an emerging and multidisciplinary field that is of great interest to
manufacturers in medicine, biotechnology, and chemistry, as it provides unique tools for the …

Microfluidic chips: recent advances, critical strategies in design, applications and future perspectives

P Pattanayak, SK Singh, M Gulati, S Vishwas… - Microfluidics and …, 2021 - Springer
Microfluidic chip technology is an emerging tool in the field of biomedical application.
Microfluidic chip includes a set of groves or microchannels that are engraved on different …

Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment

G Huang, F Li, X Zhao, Y Ma, Y Li, M Lin, G Jin… - Chemical …, 2017 - ACS Publications
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

Synthesis, properties, and biomedical applications of gelatin methacryloyl (GelMA) hydrogels

K Yue, G Trujillo-de Santiago, MM Alvarez, A Tamayol… - Biomaterials, 2015 - Elsevier
Gelatin methacryloyl (GelMA) hydrogels have been widely used for various biomedical
applications due to their suitable biological properties and tunable physical characteristics …

Functionalization, preparation and use of cell-laden gelatin methacryloyl–based hydrogels as modular tissue culture platforms

D Loessner, C Meinert, E Kaemmerer, LC Martine… - Nature protocols, 2016 - nature.com
Progress in advancing a system-level understanding of the complexity of human tissue
development and regeneration is hampered by a lack of biological model systems that …

A liver-on-a-chip platform with bioprinted hepatic spheroids

NS Bhise, V Manoharan, S Massa, A Tamayol… - …, 2016 - iopscience.iop.org
The inadequacy of animal models in correctly predicting drug and biothreat agent toxicity in
humans has resulted in a pressing need for in vitro models that can recreate the in vivo …

Interplay between materials and microfluidics

X Hou, YS Zhang, GT Santiago, MM Alvarez… - Nature Reviews …, 2017 - nature.com
Developments in the field of microfluidics have triggered technological revolutions in many
disciplines, including chemical synthesis, electronics, diagnostics, single-cell analysis, micro …

Hydrogel bioprinted microchannel networks for vascularization of tissue engineering constructs

LE Bertassoni, M Cecconi, V Manoharan, M Nikkhah… - Lab on a Chip, 2014 - pubs.rsc.org
Vascularization remains a critical challenge in tissue engineering. The development of
vascular networks within densely populated and metabolically functional tissues facilitate …

Organ‐on‐a‐chip platforms: a convergence of advanced materials, cells, and microscale technologies

S Ahadian, R Civitarese, D Bannerman… - Advanced …, 2018 - Wiley Online Library
Significant advances in biomaterials, stem cell biology, and microscale technologies have
enabled the fabrication of biologically relevant tissues and organs. Such tissues and organs …

Tissue Engineering Approaches in the Design of Healthy and Pathological In Vitro Tissue Models

S Caddeo, M Boffito, S Sartori - Frontiers in bioengineering and …, 2017 - frontiersin.org
In the tissue engineering (TE) paradigm, engineering and life sciences tools are combined
to develop bioartificial substitutes for organs and tissues, which can in turn be applied in …