The β-thalassemias are a group of hereditary hematological diseases caused by over 300
mutations of the adult β-globin gene. Together with sickle cell anemia, thalassemia …

Furanocoumarins are a class of natural compounds produced by several plants, including
those consumed by humans. They have been used medicinally in eastern countries for …

Gene editing by the CRISPR-Cas9 nuclease system technology can be considered among
the most promising strategies to correct hereditary mutations in a variety of monogenic …

β-thalassemias are among the most common inherited hemoglobinopathies worldwide and
are the result of autosomal mutations in the gene encoding β-globin, causing an absence or …

The major physiological regulators of aldosterone production from the adrenal zona
glomerulosa are potassium and angiotensin II; other acute regulators include …

Natural products frequently exert pharmacological activities. The present review gives an
overview of the ethnobotany, phytochemistry and pharmacology of the Cedrus genus, eg …

The involvement of microRNAs in the control of repressors of human γ-globin gene
transcription has been firmly demonstrated, as described for the miR-486-3p mediated down …

Abstract Human gammaherpesviruses including Epstein–Barr virus (EBV) and Kaposi's
sarcoma-associated herpesvirus (KSHV) are important pathogens as they persist in the host …

Thalassemia and sickle-cell anemia (SCA) present a major public health problem in
countries where the number of carriers and affected individuals is high. As a result of the …

Angelicin is structurally related to psoralens, a well-known chemical class of
photosensitizers used for its antiproliferative activity in treatment of different skin diseases …