Researchers worldwide are taking advantage of novel, commercially available,
technologies, such as ion mobility mass spectrometry (IM‐MS), for metabolomics and …

Hydrophilic interaction chromatography (HILIC) is an emerging separation mode of liquid
chromatography (LC). Using highly hydrophilic stationary phases capable of retaining …

Metabolomics is a rapidly evolving analytical approach in life and health sciences. The
structural elucidation of the metabolites of interest remains a major analytical challenge in …

The past decades of advancements in NMR have made it a very powerful tool for metabolic
research. Despite its limitations in sensitivity relative to mass spectrometric techniques, NMR …

The metabolome is the set of small molecular mass compounds found in biological media,
and metabolomics, which refers to as the analysis of metabolome in a given biological …

Alzheimer's disease (AD) is the most common cause of adult dementia. Yet the complete set
of molecular changes accompanying this inexorable, neurodegenerative disease remains …

Introduction As large scale metabolic phenotyping is increasingly employed in preclinical
studies and in the investigation of human health and disease the current LC–MS/MS …

Experts and suppliers continue to make advances in the application of theory, capabilities,
and practice of highperformance liquid chromatography (HPLC). It is one of the most often …

The paper reports the development of a multianalyte method and its application in metabolic
profiling of biological fluids. The initial aim of the method was the quantification of …

Preprocessing of liquid chromatography-mass spectrometry (LC-MS) raw data facilitates
downstream statistical and biological data analyses. In the case of targeted LC-MS data …