Growing evidences suggest that the fibroblast growth factor/FGF receptor (FGF/FGFR)
signaling has crucial roles in a multitude of processes during embryonic development and …

Regulated fibroblast growth factor (FGF) signalling is a prerequisite for the correct
development and homeostasis of articular cartilage, as evidenced by the fact that aberrant …

Evolved resistance to tyrosine kinase inhibitor (TKI)-targeted therapies remains a major
clinical challenge. In epidermal growth factor receptor (EGFR) mutant non-small-cell lung …

Receptor tyrosine kinases (RTKs) are single-span transmembrane receptors in which
relatively conserved intracellular kinase domains are coupled to divergent extracellular …

Fibroblast growth factors (FGFs) act as key signalling molecules in brain development,
maintenance, and repair. They influence the intricate relationship between myelinating cells …

FGF19 signaling through the FGFR4/β-klotho receptor complex has been shown to be a key
driver of growth and survival in a subset of hepatocellular carcinomas, making selective …

Fibroblast growth factor (FGF) 23 produced by bone is a hormone that decreases serum
phosphate (Pi). Reflecting its central role in Pi control, serum FGF23 is tightly regulated by …

The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …

Herein, we report a nongenetic and real-time approach for imaging protein dimerization on
living cell surfaces by aptamer recognition and proximity-induced DNA assembly. We use …

Fibroblast growth factors (FGFs) are a large family of secretory molecules that act through
tyrosine kinase receptors known as FGF receptors. They play crucial roles in a wide variety …