2H-Pyran-2-ones and their annelated analogs as multifaceted building blocks for the fabrication of diverse heterocycles

R Pratap, VJ Ram - Tetrahedron, 2017 - Elsevier
Abstract 2H-Pyran-2-ones are widely present in nature and found as either isolated or in
fused form. Depending on the fusion of benzene ring, pyran can give coumarins …

Pd-Catalyzed Asymmetric Allylic Substitution Cascade of Substituted 4-Hydroxy-2H-pyrones with meso-Allyl Dicarbonates

Y Zheng, S Dong, K Xu, D Liu, W Zhang - Organic Letters, 2022 - ACS Publications
An efficient Pd-catalyzed asymmetric allylic substitution cascade of 4-hydroxy-2 H-pyrones
with meso-allyl dicarbonates has been developed for the synthesis of kinetic chiral …

Design, Synthesis, and Anticancer Activity of 3H–benzo [f] chromen‐3‐one Derivatives

R Soni, S Umar, NN Shah… - Journal of …, 2017 - Wiley Online Library
A series of substituted aminomethylbenzocoumarin derivatives 8a–i have been synthesized,
characterized, and structure of compound 8g was confirmed by X‐ray single crystal analysis …

Pd-Catalyzed Asymmetric Allylic Substitution Cascade via Desymmetrization for the Construction of Chiral Polyheterocycles

X Kou, Y Xu, S Dong, H Liu, D Liu… - Pharmaceutical …, 2024 - thieme-connect.com
Chiral polyheterocycles represent an important class of compounds because of their
prevalence in bioactive natural products and chiral drugs. Pd-catalyzed allylic substitution is …

Coumestans: Synthesis, isolation, and bioactivity

R Patre, SG Tilve, MM Naik - Asian Journal of Organic Chemistry - Wiley Online Library
Coumestans are tetracyclic heterocycles having a coumarin ring and a benzofuran ring
fused together, sharing a common C= C bond. A large number of oxygenated coumarins …

The IC-50-time evolution is a new model to improve drug responses consistency of large scale studies

A ALILECHE - F1000Research, 2022 - f1000research.com
Large-scale studies combining hundreds of cancer cell lines and many cancer drugs, with
their promises and challenges, represent a new development in the in vitro screening of …

[PDF][PDF] Synthetic Studies in Oxygen Heterocycles

MM Naik - 2018 - irgu.unigoa.ac.in
Molecular iodine in the recent years has emerged as an attractive tool in the field of synthetic
organic chemistry. Being an environmentally benign chemical, it has been extensively …

[PDF][PDF] ISSN 0975-413X CODEN (USA): PCHHAX

MF Khan, S Aktar, RB Rashid, MA Rashid - researchgate.net
Amino-3-cyano-4H-chromen-4-yl)-phosphonates 4a-e were synthesized on reacting
substituted salicylaldehydes, malononitrile, and diethylphosphite via ultrasound irradiation …

[引用][C] In silico design and modeling of coumarin derivatives as selective monoamine oxidase a inhibitors

D Karaman - 2014 - Fen Bilimleri Enstitüsü