Telomere shortening is a well-known hallmark of both cellular senescence and organismal
aging. An accelerated rate of telomere attrition is also a common feature of age-related …

Osteoarthritis is a common age-related joint degenerative disease. Pain, swelling, brief
morning stiffness, and functional limitations are its main characteristics. There are still no …

Telomeres are at the non-coding ends of linear chromosomes. Through a complex 3-
dimensional structure, they protect the coding DNA and ensure appropriate separation of …

Osteoarthritis (OA) has been recognized as an age-related degenerative disease commonly
seen in the elderly that affects the whole “organ” including cartilage, subchondral bone …

Introduction: Telomeres are nucleoprotein complexes at the ends of chromosomes that are
under the control of genetic and environmental triggers. Accelerated telomere shortening is …

The main aim of the present systematic review was to summarize the most frequently used
telomerase regulators with an impact on aging and cancer that are referred to in in vitro and …

The current review focuses on the connection of telomerase and telomeres with aging. In
this review, we describe the changes in telomerase and telomere length (TEL) during …

Telomere dynamics play a crucial role in the maintenance of chromosome integrity; changes
in telomere length may thus contribute to the development of various diseases including …

Prior research establishing that bone interacts in coordination with the bone marrow
microenvironment (BMME) to regulate hematopoietic homeostasis was largely based on …

Telomeres are part of chromatin structures containing repeated DNA sequences, which
function as protective caps at the ends of chromosomes and prevent DNA degradation and …