Antibodies and related proteins comprise one of the largest and fastest-growing classes of
protein pharmaceuticals. A majority of such molecules are monoclonal antibodies; however …

Antibody fragments without the Fc region are attracting attention in the pharmaceutical
industry due to their high ability to penetrate solid tissues, cost-effective expression using …

Glycoprotein VI is a platelet-specific collagen receptor critical for in vivo formation of arterial
thrombosis. It is also considered as an attractive target for the development of anti …

An attractive approach for designing lead antibody candidates is to mimic natural protein
interactions by grafting peptide recognition motifs into the complementarity-determining …

At present, single-chain variable fragments (scFv) of antibodies are considered one of the
most important tools in human therapies. Wide applications of antibodies are being …

abstract Recombinant antibody single-chain variable fragments (scFv) are difficult to purify
homogeneously from a protein complex mixture. The most effective, specific and fastest …

This protocol describes the design and development of recombinant monovalent antigen-
binding molecules derived from monoclonal antibodies through rapid identification and …

Poliovirus (PV)-specific intestinal IgAs are important for cessation of PV shedding in the
gastrointestinal tract following an acute infection with wild type or vaccine-derived PV …

Complex multimeric proteins such as dimeric and secretory immunoglobulin A (IgA) can be
difficult to produce in heterologous systems, although this has been achieved using several …

In the Americas and specially in Brazil, the Loxosceles intermedia, Loxosceles gaucho and
Loxosceles laeta are the three most medically relevant brown spider species, and whose …