Effect of pH on structural dynamics of HMG-CoA reductase and binding affinity to β-sitosterol

TH Fatoki - Journal of Biomolecular Structure and Dynamics, 2023 - Taylor & Francis
Abstract Human 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR; EC 1.1. 1.34)
catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic …