[HTML][HTML] Recent developments in the assessment and management of inflammatory bowel disease in childhood: a narrative review

Z Green, RM Beattie, JJ Ashton - Translational Pediatrics, 2023 - ncbi.nlm.nih.gov
Methods We present a narrative review that synthesises and summarises recent research
(2017–2022) related to pIBD. We undertook a structured search of the literature (PubMed …

[HTML][HTML] Mucosal transcriptomics highlight lncRNAs implicated in ulcerative colitis, Crohn's disease, and celiac disease

T Braun, KE Sosnovski, A Amir, M BenShoshan… - JCI insight, 2023 - ncbi.nlm.nih.gov
Abstract Ulcerative colitis (UC), Crohn's disease (CD), and celiac disease are prevalent
intestinal inflammatory disorders with nonsatisfactory therapeutic interventions. Analyzing …

Advances in endoscopy for pediatric inflammatory bowel disease

N Carman, JA Picoraro - Gastrointestinal Endoscopy Clinics, 2023 - giendo.theclinics.com
Endoscopy in the field of inflammatory bowel disease (IBD) has remained the cornerstone of
diagnostic assessment and disease monitoring for both adult and pediatric patients. As our …

GATA6-AS1 Regulates Intestinal Epithelial Mitochondrial Functions, and its Reduced Expression is Linked to Intestinal Inflammation and Less Favourable Disease …

KE Sosnovski, T Braun, A Amir, D Moshel… - Journal of Crohn's …, 2023 - academic.oup.com
Abstract Background and Aims Widespread dysregulation of long non-coding RNAs
[lncRNAs] including a reduction in GATA6-AS1 was noted in inflammatory bowel disease …

Predicting complications in paediatric ulcerative colitis: A longitudinal multicentre cohort study

M Claßen, B Schiller, J Däbritz… - Alimentary …, 2024 - Wiley Online Library
Background To prevent complications of paediatric ulcerative colitis (UC), it is critical to
understand their predictors. The Paediatric Inflammatory Bowel Disease Ahead (PIBD …

Clinical outcome of ulcerative colitis with severe onset in children: a multicenter prospective cohort study

R Nambu, K Arai, T Kudo, T Murakoshi… - Journal of …, 2023 - Springer
Background As best practices for treating children with severe-onset ulcerative colitis remain
controversial in the era of biologic agents, we prospectively investigated treatments and …

Targeted Assessment of Mucosal Immune Gene Expression Predicts Clinical Outcomes in Children with Ulcerative Colitis

K Clarkston, R Karns, AG Jegga… - Journal of Crohn's …, 2022 - academic.oup.com
Abstract Background and Aims We aimed to determine whether a targeted gene expression
panel could predict clinical outcomes in paediatric ulcerative colitis [UC] and investigated …

Diagnosis and Treatment of Pouch Disorders in Children: A Systematic Review

P Nallapaneni, JA Picoraro - Diseases of the Colon & Rectum, 2024 - journals.lww.com
BACKGROUND: Restorative proctocolectomy and IPAA have become the surgical
procedure of choice in pediatric patients with medically refractory colitis or familial …

Role of ileal diversion in pediatric inflammatory bowel disease

AA Simard, S Kotamraju, JR DeFazio… - Journal of Pediatric …, 2024 - Wiley Online Library
Surgical intervention is often indicated in pediatric inflammatory bowel disease (IBD) for
medically refractory disease or complications of severe disease. Specifically, surgical …

[HTML][HTML] Tofacitinib to Treat Severe Acute Refractory Colitis in a Teenager: Case Report and Review of the Literature

C Girard, M Dirks, C Deslandres - JPGN reports, 2022 - journals.lww.com
Objectives: Acute severe colitis (ASC) may occur within 3 months of ulcerative colitis
diagnosis in 9%–15% of children and the rate of colectomy is up to 40%–50% within 5 years …