Neurogranin (Ng) is a small protein usually expressed in granule-like structures in pyramidal
cells of the hippocampus and cortex. However, its clinical value is not fully clear so far …

Neuroinflammation, characterized by a complex interplay among innate and adaptive
immune responses within the central nervous system (CNS), is crucial in responding to …

Among emerging arthropod-borne viruses (arbovirus), West Nile virus (WNV) is a flavivirus
that can be associated with severe neuroinvasive infections in humans. In 2018, the …

The virology of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and the
human immune response to the virus are under vigorous investigation. There are now …

Neuroinflammation and synaptodendritic damage represent the pathological hallmarks of
HIV-1 associated cognitive disorders (HAND). The post-synaptic protein neurogranin (Nrgn) …

HIV-1 selectively disrupts neuronal integrity within specific brain regions, reflecting
differences in viral tropism and/or the regional differences in the vulnerability of distinct …

We determined the prevalence of Alzheimer's disease (AD) pathological hallmarks, amyloid-
β and phosphorylated-Tau, in autopsied brains of 49 people with HIV (PWH)(ages: 50–68; …

HIV‐associated neurocognitive disorder affects about half of HIV‐infected patients. HIV
impairs neuronal function through indirect mechanisms mainly mediated by inflammatory …

People living with human immunodeficiency virus (HIV)(PLWH) are at high risk of
neurocognitive impairment. The pathogenesis of neurocognitive impairment remains …

While current therapeutic strategies for people living with human immunodeficiency virus
type 1 (HIV-1) suppress virus replication peripherally, viral proteins such as transactivator of …