Understanding how individual neurons integrate the thousands of synaptic inputs they
receive is critical to understanding how the brain works. Modeling studies in silico and …

Retinal bipolar cells are the first'projection neurons' of the vertebrate visual system—all of
the information needed for vision is relayed by this intraretinal connection. Each of the at …

The active electrical properties of dendrites shape neuronal input and output and are
fundamental to brain function. However, our knowledge of active dendrites has been almost …

The mammalian retina is an important model system for studying neural circuitry: Its role in
sensation is clear, its cell types are relatively well defined, and its responses to natural …

Half a century since their discovery by Llinás and colleagues, dendritic spikes have been
observed in various neurons in different brain regions, from the neocortex and cerebellum to …

Images projected onto the retina of an animal eye are rarely still. Instead, they usually
contain motion signals originating either from moving objects or from retinal slip caused by …

Neuronal circuit asymmetries are important components of brain circuits, but the molecular
pathways leading to their establishment remain unknown. Here we found that the mutation …

The apical tuft is the most remote area of the dendritic tree of neocortical pyramidal neurons.
Despite its distal location, the apical dendritic tuft of layer 5 pyramidal neurons receives …

Synaptic NMDA receptors can produce powerful dendritic supralinearities that expand the
computational repertoire of single neurons and their respective circuits. This form of …

Visual motion on the retina activates a cohort of retinal ganglion cells (RGCs). This
population activity encodes multiple streams of information extracted by parallel retinal …