Erythropoietin-producing human hepatocellular receptors (EPHs) compose the largest
known subfamily of receptor tyrosine kinases (RTKs). They bind and interact with the EPH …

Aberrant expression of different family members of the Eph/ephrin system, which comprises
the Eph receptors (Ephs) and their ligands (ephrins), has been implicated in various …

Background Erythropoietin-producing hepatocellular (EPH) receptors are the largest known
family of receptor tyrosine kinases characterized in humans. These proteins are involved in …

Pediatric neoplasms represent a complex group of malignancies that pose unique
challenges in terms of diagnosis, treatment, and understanding of the underlying molecular …

Ephrin receptors (Ephs) are receptor tyrosine kinases (RTKs) implicated in tissue
development and homeostasis, and they are aberrantly expressed in tumors. Here …

BACKGROUND: Eph receptors comprise the largest group of the receptor tyrosine kinase
(RTK) family, and Eph receptors interacting with their ligand ephrins play an important role in …

RET, BRAF and other protein kinases have been identified as major molecular players in
thyroid cancer. To identify novel kinases required for the viability of thyroid carcinoma cells …

Abstract Ephrin Type-A Receptor 3 (EphA3) and Ephrin Type-B Receptor 6 (EphB6) belong
to the ephrin receptor group consisting of the largest subset of receptor tyrosine kinases …

Purpose Gross extrathyroidal extension (gETE) into major vessel is considered the most
advanced stage of the locally advanced papillary thyroid cancer (PTC). Surgical intervention …

A germline mutation in cancer predisposing genes is known to increase the risk of more than
one tumor type. In order to find loci associated with many types of cancer, a genome-wide …