Objective: This clinical practice guideline addresses the diagnosis and treatment of primary
adrenal insufficiency. Participants: The Task Force included a chair, selected by The Clinical …

Adrenal insufficiency (AI) is a condition characterized by an absolute or relative deficiency of
adrenal cortisol production. Primary AI (PAI) is rare and is caused by direct adrenal failure …

Primary adrenal insufficiency (PAI), or Addison's disease, is a rare, potentially deadly, but
treatable disease. Most cases of PAI are caused by autoimmune destruction of the adrenal …

Adrenal insufficiency is the clinical manifestation of deficient production or action of
glucocorticoids, with or without deficiency also in mineralocorticoids and adrenal androgens …

Primary ovarian insufficiency (POI) is characterized by a loss of ovarian function before the
age of 40 and account for one major cause of female infertility. POI relevance is continuously …

Premature ovarian insufficiency (POI), previously known as premature ovarian failure or
premature menopause, is defined as loss of ovarian function before the age of 40 years. The …

Purpose Primary ovarian insufficiency (POI) represents ovarian dysfunction related to very
early aging of the ovaries. While the cause of POI in a majority of clinical cases remains …

The normal function of ovaries, along with the secretion of sex hormones, is among the most
important endocrine factors that maintain the female sexual characteristics and promote …

Background Addison's disease (AD) is a rare disorder and among adult population in
developed countries is most commonly caused by autoimmunity. In contrast, in children …

Premature ovarian insufficiency (POI) is a clinical syndrome defined by loss of ovarian
activity before the age of 40 years and has a potentially devastating effect upon women's …