This review is focused on the structural and physicochemical aspects of metal cation
coordination to G-Quadruplexes (GQ) and their effects on GQ stability and conformation. G …

Abstract G-quadruplexes (G4s) are extremely stable DNA or RNA secondary structures
formed by sequences rich in guanine. These structures are implicated in many essential …

Abstract Guanine-quadruplexes (G4s) are non-canonical four-stranded structures that can
be formed in guanine (G) rich nucleic acid sequences. A great number of G-rich sequences …

We introduce RNA G-quadruplex sequencing (rG4-seq), a transcriptome-wide RNA G-
quadruplex (rG4) profiling method that couples rG4-mediated reverse transcriptase stalling …

Pervasive transcription occurs in the human genome to generate thousands of RNA
transcripts, and accumulating evidence suggested that the RNA molecules, without protein …

Abstract RNA G-quadruplexes (G4s) are formed by G-rich RNA sequences in protein-coding
(mRNA) and non-coding (ncRNA) transcripts that fold into a four-stranded conformation …

G-rich sequences in DNA and RNA have a propensity to fold into stable secondary
structures termed G-quadruplexes. G-quadruplex forming sequences are widespread …

G‐quadruplexes are secondary structures formed in G‐rich sequences in DNA and RNA.
Considerable research over the past three decades has led to in‐depth insight into these …

Hepatocellular carcinoma (HCC) is one of the most frequently occurring cancers with poor
prognosis, and novel diagnostic or prognostic biomarkers and therapeutic targets for HCC …

G-quadruplexes are non-canonical secondary structures found in guanine rich regions of
DNA and RNA. Reports have indicated the wide occurrence of RNA G-quadruplexes across …