Cerebral microcirculation, perivascular unit, and glymphatic system: role of aquaporin-4 as the gatekeeper for water homeostasis

J Szczygielski, M Kopańska, A Wysocka… - Frontiers in …, 2021 - frontiersin.org
In the past, water homeostasis of the brain was understood as a certain quantitative
equilibrium of water content between intravascular, interstitial, and intracellular spaces …

Effectiveness of lumbar cerebrospinal fluid drain among patients with aneurysmal subarachnoid hemorrhage: a randomized clinical trial

S Wolf, D Mielke, C Barner, V Malinova, T Kerz… - JAMA …, 2023 - jamanetwork.com
Importance After aneurysmal subarachnoid hemorrhage, the use of lumbar drains has been
suggested to decrease the incidence of delayed cerebral ischemia and improve long-term …

Two-photon microscopy: application advantages and latest progress for in vivo imaging of neurons and blood vessels after ischemic stroke

J Li, X Wu, Y Fu, H Nie, Z Tang - Reviews in the Neurosciences, 2023 - degruyter.com
Two-photon microscopy (TPM) plays an important role in the study of the changes of the two
important components of neurovascular units (NVU)–neurons and blood vessels after …

Transcranial direct current stimulation enhances neuroplasticity and accelerates motor recovery in a stroke mouse model

V Longo, SA Barbati, A Re, F Paciello, M Bolla… - Stroke, 2022 - Am Heart Assoc
Background: More effective strategies are needed to promote poststroke functional recovery.
Here, we evaluated the impact of bihemispheric transcranial direct current stimulation …

Optogenetic spreading depolarizations do not worsen acute ischemic stroke outcome

K Sugimoto, J Yang, P Fischer, T Takizawa, IA Mulder… - Stroke, 2023 - Am Heart Assoc
Background: Spreading depolarizations (SDs) are believed to contribute to injury
progression and worsen outcomes in focal cerebral ischemia because exogenously induced …

Effects of caffeine on intracranial pressure and pain perception in freely moving rats

IME Israelsen, CSJ Westgate… - … : The Journal of …, 2023 - Wiley Online Library
Objective Caffeine, a non‐selective adenosine receptor (AR) antagonist, is the most
consumed psychostimulant in the world. Caffeine has been suggested to regulate …

Mild hypothermia reduces spreading depolarizations and infarct size in a swine model

M Kentar, FL Ramirez-Cuapio… - Journal of Cerebral …, 2023 - journals.sagepub.com
Spreading depolarizations (SDs) have been linked to infarct volume expansion following
ischemic stroke. Therapeutic hypothermia provides a neuroprotective effect after ischemic …

Analysis of cerebral spinal fluid drainage and intracranial pressure peaks in patients with subarachnoid hemorrhage

A Früh, P Truckenmüller, D Wasilewski, P Vajkoczy… - Neurocritical Care, 2024 - Springer
Background After aneurysmal subarachnoid hemorrhage (aSAH), elevated intracranial
pressure (ICP) due to disrupted cerebrospinal fluid (CSF) dynamics is a critical concern. An …

Cerebrovascular pressure reactivity according to long-pressure reactivity index during spreading depolarizations in aneurysmal subarachnoid hemorrhage

R Sanchez-Porras, FL Ramírez-Cuapio, N Hecht… - Neurocritical Care, 2023 - Springer
Background Spreading depolarization (SD) has been linked to the impairment of
neurovascular coupling. However, the association between SD occurrence and …

Oxyhemoglobin and cerebral blood flow transients detect infarction in rat focal brain ischemia

J Luckl, W Baker, K Boda, M Emri, AG Yodh… - Neuroscience, 2023 - Elsevier
Spreading depolarizations (SD) refer to the near-complete depolarization of neurons that is
associated with brain injuries such as ischemic stroke. The present gold standard for SD …