Modern drug design aims to discover novel lead compounds with attractable chemical
profiles to enable further exploration of the intersection of chemical space and biological …

In light of missing systematic reviews in the literature, the objective of this paper is to present
the contemporary knowledge on the molecular biology of vestibular schwannomas (VS) …

Vestibular schwannomas (VSs), the most common tumors of the cerebellopontine angle,
arise from Schwann cells lining the vestibular nerve. Pharmacotherapies against VS are …

BACKGROUND: The vestibular nerve is the predilection site for schwannomas. Few
transcriptomic studies have been performed on solely sporadic vestibular schwannomas …

Vestibular schwannoma (VS), although a benign intracranial tumor, causes morbidities by
brainstem compression. Since chemotherapy is not very effective in most Nf2-negative …

Mussels of the genus Mytilus are widely used in environmental monitoring. They can
develop a leukaemia-like disease, haemic neoplasia, which could be induced, in part, by …

Recent studies have shed considerable light into schwannomas. To date, only merlin has
been identified as a hallmark or pathogenesis of both sporadic and NF2-related …

Vestibular schwannomas (VSs) are benign tumors arising from eighth cranial nerve and
most often occur sporadically in individuals of middle age group. Sporadic VSs are rarely …

Chapter 7 deals with neuroblastoma (NB) and related tumors. The specific genetic events
responsible for NB development have not been established, even though several changes …

A total of 40 human brain tumor samples were analyzed for tumor-specific alterations at the
RB1 gene locus. Gliomas were more prevalent in younger males and meningiomas in older …