Arsenic is a well-recognized environmental contaminant that occurs naturally through
geogenic processes in the aquifer. More than 200 million people around the world are …

Human exposure to toxic heavy metals is a global challenge. Concurrent exposure of heavy
metals, such as lead (Pb), cadmium (Cd), arsenic (As) and methylmercury (MeHg) are …

High arsenic (As) levels in food and drinking water, or under some occupational conditions,
can precipitate chronic toxicity and in some cases cancer. Millions of people are exposed to …

Parkinson's disease (PD) is a deliberately progressive neurological disorder, arises due to
degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNpc). The …

Ellagic acid (EA) is a dietary polyphenol present in various fruits, vegetables, herbs, and
nuts. It exists either independently or as part of complex structures, such as ellagitannins …

Neurological disorders such as stroke, Alzheimer's and Parkinson's diseases are associated
with high morbidity and mortality, and few or no effective options are available for their …

Abstract Purpose of Review Mitochondria play various roles that are important for cell
function and survival; therefore, significant mitochondrial dysfunction may have chronic …

Metals play important roles in the human body, maintaining cell structure and regulating
gene expression, neurotransmission, and antioxidant response, to name a few. However …

Triptolide (TP), a major active and toxic ingredient isolated from the traditional Chinese herb
Tripterygium wilfordii Hook f.(TWHF). A widespread application of TP raises the question on …

Significance: Essential metals such as copper, iron, manganese, and zinc play a role as
cofactors in the activity of a wide range of processes involved in cellular homeostasis and …