Insights into medicinal attributes of imidazo[1,2‐a]pyridine derivatives as anticancer agents
Cancer ranks among the most life‐threatening diseases worldwide and is continuously
affecting all age groups. Consequently, many research studies are being carried out to …
affecting all age groups. Consequently, many research studies are being carried out to …
Fragment-based design and synthesis of coumarin-based thiazoles as dual c-MET/STAT-3 inhibitors for potential antitumor agents
Abstract c-MET and STAT-3 are significant targets for cancer treatments. Here, we describe
a class of very effective dual STAT-3 and c-MET inhibitors with coumarin-based thiazoles …
a class of very effective dual STAT-3 and c-MET inhibitors with coumarin-based thiazoles …
Comprehensive prediction and analysis of human protein essentiality based on a pre-trained protein large language model
Human essential genes and their protein products are indispensable for the viability and
development of the individuals. Thus, it is quite important to decipher the essential proteins …
development of the individuals. Thus, it is quite important to decipher the essential proteins …